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Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359.
Crüsemann M, Reher R, Schamari I, Brachmann AO, Ohbayashi T, Kuschak M, Malfacini D, Seidinger A, Pinto-Carbó M, Richarz R, Reuter T, Kehraus S, Hallab A, Attwood M, Schiöth HB, Mergaert P, Kikuchi Y, Schäberle TF, Kostenis E, Wenzel D, Müller CE, Piel J, Carlier A, Eberl L, König GM. Crüsemann M, et al. Among authors: seidinger a. Angew Chem Int Ed Engl. 2018 Jan 15;57(3):836-840. doi: 10.1002/anie.201707996. Epub 2017 Dec 20. Angew Chem Int Ed Engl. 2018. PMID: 29194875
Macrocyclic Gq Protein Inhibitors FR900359 and/or YM-254890-Fit for Translation?
Schlegel JG, Tahoun M, Seidinger A, Voss JH, Kuschak M, Kehraus S, Schneider M, Matthey M, Fleischmann BK, König GM, Wenzel D, Müller CE. Schlegel JG, et al. Among authors: seidinger a. ACS Pharmacol Transl Sci. 2021 Feb 19;4(2):888-897. doi: 10.1021/acsptsci.1c00021. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2021. PMID: 33860209 Free PMC article.
The β2 agonist terbutaline specifically decreases pulmonary arterial pressure under normoxia and hypoxia via α adrenoceptor antagonism.
Neumann V, Knies R, Seidinger A, Simon A, Lorenz K, Matthey M, Breuer J, Wenzel D. Neumann V, et al. Among authors: seidinger a. FASEB J. 2018 May;32(5):2519-2530. doi: 10.1096/fj.201700684RR. Epub 2018 Jan 2. FASEB J. 2018. PMID: 29295855
Pulmonary hypertension is a severe, incurable disease with a poor prognosis. Although treatment regimens have improved during the last 2 decades, current pharmacologic strategies are limited and focus on the modulation of only a few pathways related to endoth …
Pulmonary hypertension is a severe, incurable disease with a poor prognosis. Although treatment regimens have improved during …
Tumor-Promoted Changes in Pediatric Brain Histology Can Be Distinguished from Normal Parenchyma by Desorption Electrospray Ionization Mass Spectrometry Imaging.
Seidinger AL, Silva FLT, Euzébio MF, Krieger AC, Meidanis J, Gutierrez JM, Bezerra TMS, Queiroz L, Silva AAR, Hoffmann IL, Daiggi CMM, Tedeschi H, Eberlin MN, Eberlin LS, Yunes JA, Porcari AM, Cardinalli IA. Seidinger AL, et al. Biomedicines. 2024 Nov 13;12(11):2593. doi: 10.3390/biomedicines12112593. Biomedicines. 2024. PMID: 39595159 Free PMC article.
11p15 Epimutations in Pediatric Embryonic Tumors: Insights from a Methylome Analysis.
Silva FLT, Ruas JS, Euzébio MF, Hoffmann IL, Junqueira T, Tedeschi H, Pereira LH, Cassone AE, Cardinalli IA, Seidinger AL, Jotta PY, Maschietto M. Silva FLT, et al. Among authors: seidinger al. Cancers (Basel). 2023 Aug 25;15(17):4256. doi: 10.3390/cancers15174256. Cancers (Basel). 2023. PMID: 37686532 Free PMC article.
26 results