Zhang Y - Search Results

1

Synthesis and biological characterization of ubenimex-fluorouracil conjugates for anti-cancer therapy.

Jiang Y, Li X, Hou J, Huang Y, Wang X, Jia Y, Wang Q, Xu W, Zhang J, Zhang Y. Jiang Y, et al. Among authors: zhang j, zhang y. Eur J Med Chem. 2018 Jan 1;143:334-347. doi: 10.1016/j.ejmech.2017.11.074. Epub 2017 Dec 1. Eur J Med Chem. 2018. PMID: 29202398

2

Progress on kinesin spindle protein inhibitors as anti-cancer agents.

Zhang Y, Xu W. Zhang Y, et al. Anticancer Agents Med Chem. 2008 Aug;8(6):698-704. Anticancer Agents Med Chem. 2008. PMID: 18690830 Review.

3

The structure and function of histone deacetylases: the target for anti-cancer therapy.

Zhang Y, Fang H, Jiao J, Xu W. Zhang Y, et al. Curr Med Chem. 2008;15(27):2840-9. doi: 10.2174/092986708786242796. Curr Med Chem. 2008. PMID: 18991639 Review.

4

Design, synthesis and preliminary activity assay of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as novel Histone deacetylases (HDACs) inhibitors.

Zhang Y, Feng J, Liu C, Zhang L, Jiao J, Fang H, Su L, Zhang X, Zhang J, Li M, Wang B, Xu W. Zhang Y, et al. Among authors: zhang l, zhang j, zhang x. Bioorg Med Chem. 2010 Mar 1;18(5):1761-72. doi: 10.1016/j.bmc.2010.01.060. Epub 2010 Feb 6. Bioorg Med Chem. 2010. PMID: 20171895

5

Applications and modifications of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) in peptides and peptidomimetics design and discovery.

Zhang Y, Fang H, Xu W. Zhang Y, et al. Curr Protein Pept Sci. 2010 Dec;11(8):752-8. doi: 10.2174/138920310794557691. Curr Protein Pept Sci. 2010. PMID: 21235510 Review.

6

Development of tetrahydroisoquinoline-based hydroxamic acid derivatives: potent histone deacetylase inhibitors with marked in vitro and in vivo antitumor activities.

Zhang Y, Feng J, Jia Y, Wang X, Zhang L, Liu C, Fang H, Xu W. Zhang Y, et al. Among authors: zhang l. J Med Chem. 2011 Apr 28;54(8):2823-38. doi: 10.1021/jm101605z. Epub 2011 Apr 5. J Med Chem. 2011. PMID: 21476600

7

Discovery of a tetrahydroisoquinoline-based hydroxamic acid derivative (ZYJ-34c) as histone deacetylase inhibitor with potent oral antitumor activities.

Zhang Y, Fang H, Feng J, Jia Y, Wang X, Xu W. Zhang Y, et al. J Med Chem. 2011 Aug 11;54(15):5532-9. doi: 10.1021/jm200577a. Epub 2011 Jul 11. J Med Chem. 2011. PMID: 21714538

8

Design, synthesis and biological evaluation of tyrosine-based hydroxamic acid analogs as novel histone deacetylases (HDACs) inhibitors.

Zhang Y, Feng J, Liu C, Fang H, Xu W. Zhang Y, et al. Bioorg Med Chem. 2011 Aug 1;19(15):4437-44. doi: 10.1016/j.bmc.2011.06.046. Epub 2011 Jun 21. Bioorg Med Chem. 2011. PMID: 21733698

9

Design, synthesis and primary activity assay of tripeptidomimetics as histone deacetylase inhibitors with linear linker and branched cap group.

Zhang Y, Feng J, Jia Y, Xu Y, Liu C, Fang H, Xu W. Zhang Y, et al. Eur J Med Chem. 2011 Nov;46(11):5387-97. doi: 10.1016/j.ejmech.2011.08.045. Epub 2011 Sep 8. Eur J Med Chem. 2011. PMID: 21924799

10

Development of N-Hydroxycinnamamide-Based Histone Deacetylase Inhibitors with Indole-Containing Cap Group.

Zhang Y, Yang P, Chou CJ, Liu C, Wang X, Xu W. Zhang Y, et al. ACS Med Chem Lett. 2013 Feb 14;4(2):235-238. doi: 10.1021/ml300366t. Epub 2013 Jan 8. ACS Med Chem Lett. 2013. PMID: 23493449 Free PMC article.

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