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Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells.
Regan JL, Schumacher D, Staudte S, Steffen A, Haybaeck J, Keilholz U, Schweiger C, Golob-Schwarzl N, Mumberg D, Henderson D, Lehrach H, Regenbrecht CRA, Schäfer R, Lange M. Regan JL, et al. Among authors: steffen a. Cell Rep. 2017 Dec 5;21(10):2813-2828. doi: 10.1016/j.celrep.2017.11.025. Cell Rep. 2017. PMID: 29212028 Free article.
RNA sequencing of long-term label-retaining colon cancer stem cells identifies novel regulators of quiescence.
Regan JL, Schumacher D, Staudte S, Steffen A, Lesche R, Toedling J, Jourdan T, Haybaeck J, Mumberg D, Henderson D, Győrffy B, Regenbrecht CRA, Keilholz U, Schäfer R, Lange M. Regan JL, et al. Among authors: steffen a. iScience. 2021 May 24;24(6):102618. doi: 10.1016/j.isci.2021.102618. eCollection 2021 Jun 25. iScience. 2021. PMID: 34142064 Free PMC article.
Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis.
Regan JL, Schumacher D, Staudte S, Steffen A, Lesche R, Toedling J, Jourdan T, Haybaeck J, Golob-Schwarzl N, Mumberg D, Henderson D, Győrffy B, Regenbrecht CRA, Keilholz U, Schäfer R, Lange M. Regan JL, et al. Among authors: steffen a. iScience. 2022 May 31;25(7):104498. doi: 10.1016/j.isci.2022.104498. eCollection 2022 Jul 15. iScience. 2022. PMID: 35720265 Free PMC article.
Binding Kinetics Survey of the Drugged Kinome.
Georgi V, Schiele F, Berger BT, Steffen A, Marin Zapata PA, Briem H, Menz S, Preusse C, Vasta JD, Robers MB, Brands M, Knapp S, Fernández-Montalván A. Georgi V, et al. Among authors: steffen a. J Am Chem Soc. 2018 Nov 21;140(46):15774-15782. doi: 10.1021/jacs.8b08048. Epub 2018 Nov 6. J Am Chem Soc. 2018. PMID: 30362749
Photoactivated cell-killing involving a low molecular weight, donor-acceptor diphenylacetylene.
Chisholm DR, Lamb R, Pallett T, Affleck V, Holden C, Marrison J, O'Toole P, Ashton PD, Newling K, Steffen A, Nelson AK, Mahler C, Valentine R, Blacker TS, Bain AJ, Girkin J, Marder TB, Whiting A, Ambler CA. Chisholm DR, et al. Among authors: steffen a. Chem Sci. 2019 Mar 21;10(17):4673-4683. doi: 10.1039/c9sc00199a. eCollection 2019 May 7. Chem Sci. 2019. PMID: 31123578 Free PMC article.
Synthesis, photophysical and electronic properties of tetra-donor- or acceptor-substituted ortho-perylenes displaying four reversible oxidations or reductions.
Merz J, Steffen A, Nitsch J, Fink J, Schürger CB, Friedrich A, Krummenacher I, Braunschweig H, Moos M, Mims D, Lambert C, Marder TB. Merz J, et al. Among authors: steffen a. Chem Sci. 2019 Jun 24;10(32):7516-7534. doi: 10.1039/c9sc02420d. eCollection 2019 Aug 28. Chem Sci. 2019. PMID: 31588303 Free PMC article.
669 results