Gagne R - Search Results

1

Demodifying RNA for Transcriptomic Analyses of Archival Formalin-Fixed Paraffin-Embedded Samples.

Wehmas LC, Wood CE, Gagne R, Williams A, Yauk C, Gosink MM, Dalmas D, Hao R, O'Lone R, Hester S. Wehmas LC, et al. Among authors: gagne r. Toxicol Sci. 2018 Apr 1;162(2):535-547. doi: 10.1093/toxsci/kfx278. Toxicol Sci. 2018. PMID: 29228314 Free PMC article.

2

Transcriptional Profiling of Dibenzo[def,p]chrysene-induced Spleen Atrophy Provides Mechanistic Insights into its Immunotoxicity in MutaMouse.

Chepelev NL, Long AS, Williams A, Kuo B, Gagné R, Kennedy DA, Phillips DH, Arlt VM, White PA, Yauk CL. Chepelev NL, et al. Among authors: gagne r. Toxicol Sci. 2016 Jan;149(1):251-68. doi: 10.1093/toxsci/kfv232. Epub 2015 Oct 24. Toxicol Sci. 2016. PMID: 26496743

3

High-Throughput Transcriptomic Analysis of Human Primary Hepatocyte Spheroids Exposed to Per- and Polyfluoroalkyl Substances as a Platform for Relative Potency Characterization.

Rowan-Carroll A, Reardon A, Leingartner K, Gagné R, Williams A, Meier MJ, Kuo B, Bourdon-Lacombe J, Moffat I, Carrier R, Nong A, Lorusso L, Ferguson SS, Atlas E, Yauk C. Rowan-Carroll A, et al. Among authors: gagne r. Toxicol Sci. 2021 May 27;181(2):199-214. doi: 10.1093/toxsci/kfab039. Toxicol Sci. 2021. PMID: 33772556

4

Potency Ranking of Per- and Polyfluoroalkyl Substances Using High-Throughput Transcriptomic Analysis of Human Liver Spheroids.

Reardon AJF, Rowan-Carroll A, Ferguson SS, Leingartner K, Gagne R, Kuo B, Williams A, Lorusso L, Bourdon-Lacombe JA, Carrier R, Moffat I, Yauk CL, Atlas E. Reardon AJF, et al. Among authors: gagne r. Toxicol Sci. 2021 Oct 27;184(1):154-169. doi: 10.1093/toxsci/kfab102. Toxicol Sci. 2021. PMID: 34453843

5

Thyroid hormone-regulated gene expression in juvenile mouse liver: identification of thyroid response elements using microarray profiling and in silico analyses.

Paquette MA, Dong H, Gagné R, Williams A, Malowany M, Wade MG, Yauk CL. Paquette MA, et al. Among authors: gagne r. BMC Genomics. 2011 Dec 29;12:634. doi: 10.1186/1471-2164-12-634. BMC Genomics. 2011. PMID: 22206413 Free PMC article.

6

Impact of Genomics Platform and Statistical Filtering on Transcriptional Benchmark Doses (BMD) and Multiple Approaches for Selection of Chemical Point of Departure (PoD).

Webster AF, Chepelev N, Gagné R, Kuo B, Recio L, Williams A, Yauk CL. Webster AF, et al. Among authors: gagne r. PLoS One. 2015 Aug 27;10(8):e0136764. doi: 10.1371/journal.pone.0136764. eCollection 2015. PLoS One. 2015. PMID: 26313361 Free PMC article.

7

Transcriptional profiling of the mouse hippocampus supports an NMDAR-mediated neurotoxic mode of action for benzo[a]pyrene.

Chepelev NL, Long AS, Bowers WJ, Gagné R, Williams A, Kuo B, Phillips DH, Arlt VM, White PA, Yauk CL. Chepelev NL, et al. Among authors: gagne r. Environ Mol Mutagen. 2016 Jun;57(5):350-63. doi: 10.1002/em.22020. Epub 2016 May 19. Environ Mol Mutagen. 2016. PMID: 27195522 Free PMC article.

8

Hepatic transcriptional dose-response analysis of male and female Fischer rats exposed to hexabromocyclododecane.

Farmahin R, Gannon AM, Gagné R, Rowan-Carroll A, Kuo B, Williams A, Curran I, Yauk CL. Farmahin R, et al. Among authors: gagne r. Food Chem Toxicol. 2019 Nov;133:110262. doi: 10.1016/j.fct.2018.12.032. Epub 2018 Dec 27. Food Chem Toxicol. 2019. PMID: 30594549 Free article.

9

A Modern Genotoxicity Testing Paradigm: Integration of the High-Throughput CometChip® and the TGx-DDI Transcriptomic Biomarker in Human HepaRG™ Cell Cultures.

Buick JK, Williams A, Meier MJ, Swartz CD, Recio L, Gagné R, Ferguson SS, Engelward BP, Yauk CL. Buick JK, et al. Among authors: gagne r. Front Public Health. 2021 Aug 18;9:694834. doi: 10.3389/fpubh.2021.694834. eCollection 2021. Front Public Health. 2021. PMID: 34485225 Free PMC article.

10

Transcriptional profiling of male CD-1 mouse lungs and Harderian glands supports the involvement of calcium signaling in acrylamide-induced tumors.

Chepelev NL, Gagné R, Maynor T, Kuo B, Hobbs CA, Recio L, Yauk CL. Chepelev NL, et al. Among authors: gagne r. Regul Toxicol Pharmacol. 2018 Jun;95:75-90. doi: 10.1016/j.yrtph.2018.02.005. Epub 2018 Feb 21. Regul Toxicol Pharmacol. 2018. PMID: 29475067 Free article.

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