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A small-molecule activator of kinesin-1 drives remodeling of the microtubule network.
Randall TS, Yip YY, Wallock-Richards DJ, Pfisterer K, Sanger A, Ficek W, Steiner RA, Beavil AJ, Parsons M, Dodding MP. Randall TS, et al. Among authors: beavil aj. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13738-13743. doi: 10.1073/pnas.1715115115. Epub 2017 Dec 11. Proc Natl Acad Sci U S A. 2017. PMID: 29229862 Free PMC article.
Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI.
Dhaliwal B, Yuan D, Pang MO, Henry AJ, Cain K, Oxbrow A, Fabiane SM, Beavil AJ, McDonnell JM, Gould HJ, Sutton BJ. Dhaliwal B, et al. Among authors: beavil aj. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12686-91. doi: 10.1073/pnas.1207278109. Epub 2012 Jul 16. Proc Natl Acad Sci U S A. 2012. PMID: 22802656 Free PMC article.
Structure of a patient-derived antibody in complex with allergen reveals simultaneous conventional and superantigen-like recognition.
Mitropoulou AN, Bowen H, Dodev TS, Davies AM, Bax HJ, Beavil RL, Beavil AJ, Gould HJ, James LK, Sutton BJ. Mitropoulou AN, et al. Among authors: beavil aj, beavil rl. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8707-E8716. doi: 10.1073/pnas.1806840115. Epub 2018 Aug 27. Proc Natl Acad Sci U S A. 2018. PMID: 30150373 Free PMC article.
A fluorescent biosensor reveals conformational changes in human immunoglobulin E Fc: implications for mechanisms of receptor binding, inhibition, and allergen recognition.
Hunt J, Keeble AH, Dale RE, Corbett MK, Beavil RL, Levitt J, Swann MJ, Suhling K, Ameer-Beg S, Sutton BJ, Beavil AJ. Hunt J, et al. Among authors: beavil aj, beavil rl. J Biol Chem. 2012 May 18;287(21):17459-17470. doi: 10.1074/jbc.M111.331967. Epub 2012 Mar 22. J Biol Chem. 2012. PMID: 22442150 Free PMC article.
68 results