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A small-molecule activator of kinesin-1 drives remodeling of the microtubule network.
Randall TS, Yip YY, Wallock-Richards DJ, Pfisterer K, Sanger A, Ficek W, Steiner RA, Beavil AJ, Parsons M, Dodding MP. Randall TS, et al. Among authors: sanger a. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13738-13743. doi: 10.1073/pnas.1715115115. Epub 2017 Dec 11. Proc Natl Acad Sci U S A. 2017. PMID: 29229862 Free PMC article.
The light chains of kinesin-1 are autoinhibited.
Yip YY, Pernigo S, Sanger A, Xu M, Parsons M, Steiner RA, Dodding MP. Yip YY, et al. Among authors: sanger a. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2418-23. doi: 10.1073/pnas.1520817113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884162 Free PMC article.
Adaptor protein complexes and disease at a glance.
Sanger A, Hirst J, Davies AK, Robinson MS. Sanger A, et al. J Cell Sci. 2019 Oct 21;132(20):jcs222992. doi: 10.1242/jcs.222992. J Cell Sci. 2019. PMID: 31636158 Review.
64 results