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Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome.
Deng Z, Glousker G, Molczan A, Fox AJ, Lamm N, Dheekollu J, Weizman OE, Schertzer M, Wang Z, Vladimirova O, Schug J, Aker M, Londoño-Vallejo A, Kaestner KH, Lieberman PM, Tzfati Y. Deng Z, et al. Among authors: vladimirova o. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3408-16. doi: 10.1073/pnas.1300600110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959892 Free PMC article.
HSV-1 remodels host telomeres to facilitate viral replication.
Deng Z, Kim ET, Vladimirova O, Dheekollu J, Wang Z, Newhart A, Liu D, Myers JL, Hensley SE, Moffat J, Janicki SM, Fraser NW, Knipe DM, Weitzman MD, Lieberman PM. Deng Z, et al. Among authors: vladimirova o. Cell Rep. 2014 Dec 24;9(6):2263-78. doi: 10.1016/j.celrep.2014.11.019. Epub 2014 Dec 11. Cell Rep. 2014. PMID: 25497088 Free PMC article.
Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres.
Tutton S, Azzam GA, Stong N, Vladimirova O, Wiedmer A, Monteith JA, Beishline K, Wang Z, Deng Z, Riethman H, McMahon SB, Murphy M, Lieberman PM. Tutton S, et al. Among authors: vladimirova o. EMBO J. 2016 Jan 18;35(2):193-207. doi: 10.15252/embj.201490880. Epub 2015 Dec 12. EMBO J. 2016. PMID: 26658110 Free PMC article.
CTCF interacts with the lytic HSV-1 genome to promote viral transcription.
Lang F, Li X, Vladimirova O, Hu B, Chen G, Xiao Y, Singh V, Lu D, Li L, Han H, Wickramasinghe JM, Smith ST, Zheng C, Li Q, Lieberman PM, Fraser NW, Zhou J. Lang F, et al. Among authors: vladimirova o. Sci Rep. 2017 Jan 3;7:39861. doi: 10.1038/srep39861. Sci Rep. 2017. PMID: 28045091 Free PMC article.
LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency.
De Leo A, Deng Z, Vladimirova O, Chen HS, Dheekollu J, Calderon A, Myers KA, Hayden J, Keeney F, Kaufer BB, Yuan Y, Robertson E, Lieberman PM. De Leo A, et al. Among authors: vladimirova o. PLoS Pathog. 2019 Jan 25;15(1):e1007489. doi: 10.1371/journal.ppat.1007489. eCollection 2019 Jan. PLoS Pathog. 2019. PMID: 30682185 Free PMC article.
ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization.
Li F, Deng Z, Zhang L, Wu C, Jin Y, Hwang I, Vladimirova O, Xu L, Yang L, Lu B, Dheekollu J, Li JY, Feng H, Hu J, Vakoc CR, Ying H, Paik J, Lieberman PM, Zheng H. Li F, et al. Among authors: vladimirova o. EMBO J. 2019 Oct 1;38(19):e96659. doi: 10.15252/embj.201796659. Epub 2019 Aug 27. EMBO J. 2019. PMID: 31454099 Free PMC article.
60 results