Brown H - Search Results

1

Retraction Note: Transgenic mice overexpressing the ALS-linked protein Matrin 3 develop a profound muscle phenotype.

Moloney C, Rayaprolu S, Howard J, Fromholt S, Brown H, Collins M, Cabrera M, Duffy C, Siemienski Z, Miller D, Swanson MS, Notterpek L, Borchelt DR, Lewis J. Moloney C, et al. Among authors: brown h. Acta Neuropathol Commun. 2017 Dec 13;5(1):97. doi: 10.1186/s40478-017-0502-0. Acta Neuropathol Commun. 2017. PMID: 29237481 Free PMC article.

2

Transgenic mice overexpressing the ALS-linked protein Matrin 3 develop a profound muscle phenotype.

Moloney C, Rayaprolu S, Howard J, Fromholt S, Brown H, Collins M, Cabrera M, Duffy C, Siemienski Z, Miller D, Swanson MS, Notterpek L, Borchelt DR, Lewis J. Moloney C, et al. Among authors: brown h. Acta Neuropathol Commun. 2016 Nov 18;4(1):122. doi: 10.1186/s40478-016-0393-5. Acta Neuropathol Commun. 2016. Retraction in: Acta Neuropathol Commun. 2017 Dec 13;5(1):97. doi: 10.1186/s40478-017-0502-0 PMID: 27863507 Free PMC article. Retracted.

3

Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3.

Moloney C, Rayaprolu S, Howard J, Fromholt S, Brown H, Collins M, Cabrera M, Duffy C, Siemienski Z, Miller D, Borchelt DR, Lewis J. Moloney C, et al. Among authors: brown h. Acta Neuropathol Commun. 2018 Dec 19;6(1):137. doi: 10.1186/s40478-018-0631-0. Acta Neuropathol Commun. 2018. PMID: 30563574 Free PMC article.

4

Direct and indirect mechanisms for wild-type SOD1 to enhance the toxicity of mutant SOD1 in bigenic transgenic mice.

Xu G, Ayers JI, Roberts BL, Brown H, Fromholt S, Green C, Borchelt DR. Xu G, et al. Among authors: brown h. Hum Mol Genet. 2015 Feb 15;24(4):1019-35. doi: 10.1093/hmg/ddu517. Epub 2014 Oct 9. Hum Mol Genet. 2015. PMID: 25305079 Free PMC article.

5

Substantially elevating the levels of αB-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation.

Xu G, Fromholt S, Ayers JI, Brown H, Siemienski Z, Crosby KW, Mayer CA, Janus C, Borchelt DR. Xu G, et al. Among authors: brown h. J Neurochem. 2015 May;133(3):452-64. doi: 10.1111/jnc.13022. Epub 2015 Jan 26. J Neurochem. 2015. PMID: 25557022 Free PMC article.

6

Generation of a new transgenic mouse model for assessment of tau gene silencing therapies.

Fromholt S, Reitano C, Brown H, Lewis J, Borchelt DR. Fromholt S, et al. Among authors: brown h. Alzheimers Res Ther. 2016 Sep 5;8(1):36. doi: 10.1186/s13195-016-0202-1. Alzheimers Res Ther. 2016. PMID: 27593210 Free PMC article.

7

Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.

Iradi MCG, Triplett JC, Thomas JD, Davila R, Crown AM, Brown H, Lewis J, Swanson MS, Xu G, Rodriguez-Lebron E, Borchelt DR. Iradi MCG, et al. Among authors: brown h. Sci Rep. 2018 Mar 6;8(1):4049. doi: 10.1038/s41598-018-21371-4. Sci Rep. 2018. PMID: 29511296 Free PMC article.

8

Subcellular Localization of Matrin 3 Containing Mutations Associated with ALS and Distal Myopathy.

Gallego-Iradi MC, Clare AM, Brown HH, Janus C, Lewis J, Borchelt DR. Gallego-Iradi MC, et al. Among authors: brown hh. PLoS One. 2015 Nov 3;10(11):e0142144. doi: 10.1371/journal.pone.0142144. eCollection 2015. PLoS One. 2015. PMID: 26528920 Free PMC article.

9

N-terminal sequences in matrin 3 mediate phase separation into droplet-like structures that recruit TDP43 variants lacking RNA binding elements.

Gallego-Iradi MC, Strunk H, Crown AM, Davila R, Brown H, Rodriguez-Lebron E, Borchelt DR. Gallego-Iradi MC, et al. Among authors: brown h. Lab Invest. 2019 Jul;99(7):1030-1040. doi: 10.1038/s41374-019-0260-7. Epub 2019 Apr 24. Lab Invest. 2019. PMID: 31019288 Free PMC article.

10

Experimental mutagenesis of huntingtin to map cleavage sites: different outcomes in cell and mouse models.

Tebbenkamp AT, Xu G, Siemienski ZB, Janus C, Fromholt SE, Brown HH, Swing D, Tessarollo L, Borchelt DR. Tebbenkamp AT, et al. Among authors: brown hh. J Huntingtons Dis. 2014;3(1):73-86. doi: 10.3233/JHD-130087. J Huntingtons Dis. 2014. PMID: 25062766

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