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Page 1
Communication between N terminus and loop2 tunes Orai activation.
Fahrner M, Pandey SK, Muik M, Traxler L, Butorac C, Stadlbauer M, Zayats V, Krizova A, Plenk P, Frischauf I, Schindl R, Gruber HJ, Hinterdorfer P, Ettrich R, Romanin C, Derler I. Fahrner M, et al. Among authors: butorac c. J Biol Chem. 2018 Jan 26;293(4):1271-1285. doi: 10.1074/jbc.M117.812693. Epub 2017 Dec 13. J Biol Chem. 2018. PMID: 29237733 Free PMC article.
A novel STIM1-Orai1 gating interface essential for CRAC channel activation.
Butorac C, Muik M, Derler I, Stadlbauer M, Lunz V, Krizova A, Lindinger S, Schober R, Frischauf I, Bhardwaj R, Hediger MA, Groschner K, Romanin C. Butorac C, et al. Cell Calcium. 2019 May;79:57-67. doi: 10.1016/j.ceca.2019.02.009. Epub 2019 Feb 23. Cell Calcium. 2019. PMID: 30831274 Free article.
Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
Frischauf I, Litviňuková M, Schober R, Zayats V, Svobodová B, Bonhenry D, Lunz V, Cappello S, Tociu L, Reha D, Stallinger A, Hochreiter A, Pammer T, Butorac C, Muik M, Groschner K, Bogeski I, Ettrich RH, Romanin C, Schindl R. Frischauf I, et al. Among authors: butorac c. Sci Signal. 2017 Nov 28;10(507):eaao0358. doi: 10.1126/scisignal.aao0358. Sci Signal. 2017. PMID: 29184031 Free PMC article.
Photoswitchable Inhibitor of the Calcium Channel TRPV6.
Cunha MR, Bhardwaj R, Lindinger S, Butorac C, Romanin C, Hediger MA, Reymond JL. Cunha MR, et al. Among authors: butorac c. ACS Med Chem Lett. 2019 Aug 2;10(9):1341-1345. doi: 10.1021/acsmedchemlett.9b00298. eCollection 2019 Sep 12. ACS Med Chem Lett. 2019. PMID: 31531207 Free PMC article.
Lipid-independent control of endothelial and neuronal TRPC3 channels by light.
Tiapko O, Shrestha N, Lindinger S, Guedes de la Cruz G, Graziani A, Klec C, Butorac C, Graier WF, Kubista H, Freichel M, Birnbaumer L, Romanin C, Glasnov T, Groschner K. Tiapko O, et al. Among authors: butorac c. Chem Sci. 2019 Jan 15;10(9):2837-2842. doi: 10.1039/c8sc05536j. eCollection 2019 Mar 7. Chem Sci. 2019. PMID: 30997005 Free PMC article.