Lombardo A - Search Results

1

Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.

Benedetti S, Uno N, Hoshiya H, Ragazzi M, Ferrari G, Kazuki Y, Moyle LA, Tonlorenzi R, Lombardo A, Chaouch S, Mouly V, Moore M, Popplewell L, Kazuki K, Katoh M, Naldini L, Dickson G, Messina G, Oshimura M, Cossu G, Tedesco FS. Benedetti S, et al. Among authors: lombardo a. EMBO Mol Med. 2018 Feb;10(2):254-275. doi: 10.15252/emmm.201607284. EMBO Mol Med. 2018. PMID: 29242210 Free PMC article.

2

Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors.

Follenzi A, Sabatino G, Lombardo A, Boccaccio C, Naldini L. Follenzi A, et al. Among authors: lombardo a. Hum Gene Ther. 2002 Jan 20;13(2):243-60. doi: 10.1089/10430340252769770. Hum Gene Ther. 2002. PMID: 11812281

3

In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors.

Di Natale P, Di Domenico C, Villani GR, Lombardo A, Follenzi A, Naldini L. Di Natale P, et al. Among authors: lombardo a. Eur J Biochem. 2002 Jun;269(11):2764-71. doi: 10.1046/j.1432-1033.2002.02951.x. Eur J Biochem. 2002. PMID: 12047386 Free article.

4

Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice.

Follenzi A, Battaglia M, Lombardo A, Annoni A, Roncarolo MG, Naldini L. Follenzi A, et al. Among authors: lombardo a. Blood. 2004 May 15;103(10):3700-9. doi: 10.1182/blood-2003-09-3217. Epub 2003 Dec 30. Blood. 2004. PMID: 14701690 Free article.

5

Gene therapy for a mucopolysaccharidosis type I murine model with lentiviral-IDUA vector.

Di Domenico C, Villani GR, Di Napoli D, Reyero EG, Lombardo A, Naldini L, Di Natale P. Di Domenico C, et al. Among authors: lombardo a. Hum Gene Ther. 2005 Jan;16(1):81-90. doi: 10.1089/hum.2005.16.81. Hum Gene Ther. 2005. PMID: 15703491

6

The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen-presenting cells but not by CD4+CD25+ regulatory T cells.

Annoni A, Battaglia M, Follenzi A, Lombardo A, Sergi-Sergi L, Naldini L, Roncarolo MG. Annoni A, et al. Among authors: lombardo a. Blood. 2007 Sep 15;110(6):1788-96. doi: 10.1182/blood-2006-11-059873. Epub 2007 May 10. Blood. 2007. PMID: 17495135 Free article.

7

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice.

Brown BD, Cantore A, Annoni A, Sergi LS, Lombardo A, Della Valle P, D'Angelo A, Naldini L. Brown BD, et al. Among authors: lombardo a. Blood. 2007 Dec 15;110(13):4144-52. doi: 10.1182/blood-2007-03-078493. Epub 2007 Aug 28. Blood. 2007. PMID: 17726165 Free article.

8

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery.

Lombardo A, Genovese P, Beausejour CM, Colleoni S, Lee YL, Kim KA, Ando D, Urnov FD, Galli C, Gregory PD, Holmes MC, Naldini L. Lombardo A, et al. Nat Biotechnol. 2007 Nov;25(11):1298-306. doi: 10.1038/nbt1353. Epub 2007 Oct 28. Nat Biotechnol. 2007. PMID: 17965707

9

Site-specific integration and tailoring of cassette design for sustainable gene transfer.

Lombardo A, Cesana D, Genovese P, Di Stefano B, Provasi E, Colombo DF, Neri M, Magnani Z, Cantore A, Lo Riso P, Damo M, Pello OM, Holmes MC, Gregory PD, Gritti A, Broccoli V, Bonini C, Naldini L. Lombardo A, et al. Nat Methods. 2011 Aug 21;8(10):861-9. doi: 10.1038/nmeth.1674. Nat Methods. 2011. PMID: 21857672

10

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity.

Camnasio S, Delli Carri A, Lombardo A, Grad I, Mariotti C, Castucci A, Rozell B, Lo Riso P, Castiglioni V, Zuccato C, Rochon C, Takashima Y, Diaferia G, Biunno I, Gellera C, Jaconi M, Smith A, Hovatta O, Naldini L, Di Donato S, Feki A, Cattaneo E. Camnasio S, et al. Among authors: lombardo a. Neurobiol Dis. 2012 Apr;46(1):41-51. doi: 10.1016/j.nbd.2011.12.042. Neurobiol Dis. 2012. PMID: 22405424

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