Yang Z - Search Results

1

Site-Specific Modification Using the 2'-Methoxyethyl Group Improves the Specificity and Activity of siRNAs.

Song X, Wang X, Ma Y, Liang Z, Yang Z, Cao H. Song X, et al. Among authors: yang z. Mol Ther Nucleic Acids. 2017 Dec 15;9:242-250. doi: 10.1016/j.omtn.2017.10.003. Epub 2017 Oct 7. Mol Ther Nucleic Acids. 2017. PMID: 29246303 Free PMC article.

2

Studies on aminoisonucleoside modified siRNAs: stability and silencing activity.

Li ZS, Qiao RP, Du Q, Yang ZJ, Zhang LR, Zhang PZ, Liang ZC, Zhang LH. Li ZS, et al. Bioconjug Chem. 2007 Jul-Aug;18(4):1017-24. doi: 10.1021/bc060398+. Epub 2007 Jun 1. Bioconjug Chem. 2007. PMID: 17539595

3

Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs.

Huang H, Qiao R, Zhao D, Zhang T, Li Y, Yi F, Lai F, Hong J, Ding X, Yang Z, Zhang L, Du Q, Liang Z. Huang H, et al. Among authors: yang z. Nucleic Acids Res. 2009 Dec;37(22):7560-9. doi: 10.1093/nar/gkp835. Nucleic Acids Res. 2009. PMID: 19815667 Free PMC article.

4

Exploring directional invasion of serum nuclease into siRNA duplexes by asymmetrical terminal modifications.

Huang Y, Ma Y, Guo Y, Zou L, Jin H, Zhong L, Wu Y, Zhang L, Yang Z. Huang Y, et al. Among authors: yang z. ChemMedChem. 2014 Sep;9(9):2111-9. doi: 10.1002/cmdc.201402115. Epub 2014 Jul 17. ChemMedChem. 2014. PMID: 25044832

5

D-Isonucleotide (isoNA) incorporation around cleavage site of passenger strand promotes the vibration of Ago2-PAZ domain and enhances in vitro potency of siRNA.

Huang Y, Tian M, Zhang Y, Sheng G, Chen Z, Ma Y, Chen Y, Peng Y, Zhao YL, Wang Y, Zhang L, Yang Z. Huang Y, et al. Among authors: yang z. Org Biomol Chem. 2015 Nov 28;13(44):10825-33. doi: 10.1039/c5ob01119a. Epub 2015 Aug 27. Org Biomol Chem. 2015. PMID: 26313718

6

Biological Properties of a 3',3″-Bis-Peptide-siRNA Conjugate in Vitro and in Vivo.

Fan X, Zhang Y, Liu X, He H, Ma Y, Sun J, Huang Y, Wang X, Wu Y, Zhang L, Yang Z. Fan X, et al. Among authors: yang z. Bioconjug Chem. 2016 Apr 20;27(4):1131-42. doi: 10.1021/acs.bioconjchem.6b00087. Epub 2016 Mar 23. Bioconjug Chem. 2016. PMID: 26963141

7

Isonucleotide incorporation into middle and terminal siRNA duplexes exhibits high gene silencing efficacy and nuclease resistance.

Ma Y, Liu S, Wang Y, Zhao Y, Huang Y, Zhong L, Guan Z, Zhang L, Yang Z. Ma Y, et al. Among authors: yang z. Org Biomol Chem. 2017 Jun 21;15(24):5161-5170. doi: 10.1039/c7ob01065f. Org Biomol Chem. 2017. PMID: 28585968

8

Reductive nanocomplex encapsulation of cRGD-siRNA conjugates for enhanced targeting to cancer cells.

Zhou Z, Liu S, Zhang Y, Yang X, Ma Y, Guan Z, Wu Y, Zhang L, Yang Z. Zhou Z, et al. Among authors: yang x, yang z. Int J Nanomedicine. 2017 Oct 4;12:7255-7272. doi: 10.2147/IJN.S136726. eCollection 2017. Int J Nanomedicine. 2017. PMID: 29042774 Free PMC article.

9

The Bioactivity of D-/L-Isonucleoside- and 2'-Deoxyinosine-Incorporated Aptamer AS1411s Including DNA Replication/MicroRNA Expression.

Fan X, Sun L, Li K, Yang X, Cai B, Zhang Y, Zhu Y, Ma Y, Guan Z, Wu Y, Zhang L, Yang Z. Fan X, et al. Among authors: yang x, yang z. Mol Ther Nucleic Acids. 2017 Dec 15;9:218-229. doi: 10.1016/j.omtn.2017.09.010. Epub 2017 Sep 30. Mol Ther Nucleic Acids. 2017. PMID: 29246300 Free PMC article.

10

Delivery Pathway Regulation of 3',3″-Bis-Peptide-siRNA Conjugate via Nanocarrier Architecture Engineering.

Sun J, Qiu C, Diao Y, Wei W, Jin H, Zheng Y, Wang J, Zhang L, Yang Z. Sun J, et al. Among authors: yang z. Mol Ther Nucleic Acids. 2018 Mar 2;10:75-90. doi: 10.1016/j.omtn.2017.11.002. Epub 2017 Nov 14. Mol Ther Nucleic Acids. 2018. PMID: 29499958 Free PMC article.

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