Fu W - Search Results

1

Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models.

Wei JL, Fu W, Ding YJ, Hettinghouse A, Lendhey M, Schwarzkopf R, Kennedy OD, Liu CJ. Wei JL, et al. Among authors: fu w. Arthritis Res Ther. 2017 Dec 19;19(1):280. doi: 10.1186/s13075-017-1485-8. Arthritis Res Ther. 2017. PMID: 29258611 Free PMC article.

2

Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis.

Fu W, Hu W, Shi L, Mundra JJ, Xiao G, Dustin ML, Liu CJ. Fu W, et al. FASEB J. 2017 Apr;31(4):1354-1367. doi: 10.1096/fj.201601134R. Epub 2016 Dec 23. FASEB J. 2017. PMID: 28011648 Free PMC article.

These findings define a previously unrecognized signaling pathway that underlies IL-10 production by PGRN in T(reg) cells and present new insights into the mechanisms by which PGRN resolves inflammation in inflammatory conditions and autoimmune diseases, particularly inflammatory …

These findings define a previously unrecognized signaling pathway that underlies IL-10 production by PGRN in T(reg) cells and present new in …

3

Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease.

Jian J, Chen Y, Liberti R, Fu W, Hu W, Saunders-Pullman R, Pastores GM, Chen Y, Sun Y, Grabowski GA, Liu CJ. Jian J, et al. Among authors: fu w. EBioMedicine. 2018 Feb;28:251-260. doi: 10.1016/j.ebiom.2018.01.022. Epub 2018 Jan 31. EBioMedicine. 2018. PMID: 29396296 Free PMC article.

4

p204 Is Required for Canonical Lipopolysaccharide-induced TLR4 Signaling in Mice.

Yi YS, Jian J, Gonzalez-Gugel E, Shi YX, Tian Q, Fu W, Hettinghouse A, Song W, Liu R, He M, Qi H, Yang J, Du X, Xiao G, Chen L, Liu CJ. Yi YS, et al. Among authors: fu w. EBioMedicine. 2018 Mar;29:78-91. doi: 10.1016/j.ebiom.2018.02.012. Epub 2018 Feb 16. EBioMedicine. 2018. PMID: 29472103 Free PMC article.

5

Role of ADAMTS-12 in Protecting Against Inflammatory Arthritis in Mice By Interacting With and Inactivating Proinflammatory Connective Tissue Growth Factor.

Wei JL, Fu W, Hettinghouse A, He WJ, Lipson KE, Liu CJ. Wei JL, et al. Among authors: fu w. Arthritis Rheumatol. 2018 Nov;70(11):1745-1756. doi: 10.1002/art.40552. Epub 2018 Sep 24. Arthritis Rheumatol. 2018. PMID: 29750395 Free PMC article.

6

Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis.

Liu R, Chen Y, Fu W, Wang S, Cui Y, Zhao X, Lei ZN, Hettinghouse A, Liu J, Wang C, Zhang C, Bi Y, Xiao G, Chen ZS, Liu CJ. Liu R, et al. Among authors: fu w. Ann Rheum Dis. 2019 Nov;78(11):1524-1535. doi: 10.1136/annrheumdis-2019-215543. Epub 2019 Jul 13. Ann Rheum Dis. 2019. PMID: 31302596 Free PMC article.

7

In Vitro Physical and Functional Interaction Assays to Examine the Binding of Progranulin Derivative Atsttrin to TNFR2 and Its Anti-TNFα Activity.

Fu W, Hettinghouse A, Liu CJ. Fu W, et al. Methods Mol Biol. 2021;2248:109-119. doi: 10.1007/978-1-0716-1130-2_8. Methods Mol Biol. 2021. PMID: 33185871 Free PMC article.

8

Monitoring Atsttrin-Mediated Inhibition of TNFα/NF-κβ Activation Through In Vivo Bioluminescence Imaging.

Hettinghouse A, Fu W, Liu CJ. Hettinghouse A, et al. Among authors: fu w. Methods Mol Biol. 2021;2248:201-210. doi: 10.1007/978-1-0716-1130-2_14. Methods Mol Biol. 2021. PMID: 33185877 Free PMC article.

9

Repurposing FDA-approved drugs for SARS-CoV-2 through an ELISA-based screening for the inhibition of RBD/ACE2 interaction.

Fu W, Chen Y, Wang K, Hettinghouse A, Hu W, Wang JQ, Lei ZN, Chen ZS, Stapleford KA, Liu CJ. Fu W, et al. Protein Cell. 2021 Jul;12(7):586-591. doi: 10.1007/s13238-020-00803-w. Epub 2020 Nov 18. Protein Cell. 2021. PMID: 33210243 Free PMC article. No abstract available.

10

TNFR2/14-3-3ε signaling complex instructs macrophage plasticity in inflammation and autoimmunity.

Fu W, Hu W, Yi YS, Hettinghouse A, Sun G, Bi Y, He W, Zhang L, Gao G, Liu J, Toyo-Oka K, Xiao G, Solit DB, Loke P, Liu CJ. Fu W, et al. J Clin Invest. 2021 Aug 16;131(16):e144016. doi: 10.1172/JCI144016. J Clin Invest. 2021. PMID: 34185706 Free PMC article.

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