Picard D - Search Results

1

Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol.

Abla N, Bashyam S, Charman SA, Greco B, Hewitt P, Jiménez-Díaz MB, Katneni K, Kubas H, Picard D, Sambandan Y, Sanz L, Smith D, Wang T, Willis P, Wittlin S, Spangenberg T. Abla N, et al. Among authors: picard d. ACS Med Chem Lett. 2017 Nov 28;8(12):1304-1308. doi: 10.1021/acsmedchemlett.7b00391. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29259752 Free PMC article.

2

Differences in conformational dynamics between Plasmodium falciparum and human Hsp90 orthologues enable the structure-based discovery of pathogen-selective inhibitors.

Wang T, Bisson WH, Mäser P, Scapozza L, Picard D. Wang T, et al. Among authors: picard d. J Med Chem. 2014 Mar 27;57(6):2524-35. doi: 10.1021/jm401801t. Epub 2014 Mar 3. J Med Chem. 2014. PMID: 24580531

3

Inhibition of Plasmodium falciparum Hsp90 Contributes to the Antimalarial Activities of Aminoalcohol-carbazoles.

Wang T, Mäser P, Picard D. Wang T, et al. Among authors: picard d. J Med Chem. 2016 Jul 14;59(13):6344-52. doi: 10.1021/acs.jmedchem.6b00591. Epub 2016 Jun 28. J Med Chem. 2016. PMID: 27312008

4

The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity.

Echeverria PC, Bhattacharya K, Joshi A, Wang T, Picard D. Echeverria PC, et al. Among authors: picard d. PLoS One. 2019 Feb 6;14(2):e0208287. doi: 10.1371/journal.pone.0208287. eCollection 2019. PLoS One. 2019. PMID: 30726209 Free PMC article.

5

A non-radioactive method for inexpensive quantitative RT-PCR.

Maggiolini M, Donzé O, Picard D. Maggiolini M, et al. Among authors: picard d. Biol Chem. 1999 Jun;380(6):695-7. doi: 10.1515/BC.1999.086. Biol Chem. 1999. PMID: 10430034

6

The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast system.

Liu JW, Jeannin E, Picard D. Liu JW, et al. Among authors: picard d. Biol Chem. 1999 Nov;380(11):1341-5. doi: 10.1515/BC.1999.172. Biol Chem. 1999. PMID: 10614829

7

The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest.

Abbas-Terki T, Donzé O, Picard D. Abbas-Terki T, et al. Among authors: picard d. FEBS Lett. 2000 Feb 4;467(1):111-6. doi: 10.1016/s0014-5793(00)01134-0. FEBS Lett. 2000. PMID: 10664467 Free article.

8

The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically.

Abbas-Terki T, Briand PA, Donzé O, Picard D. Abbas-Terki T, et al. Among authors: picard d. Biol Chem. 2002 Sep;383(9):1335-42. doi: 10.1515/BC.2002.152. Biol Chem. 2002. PMID: 12437126

9

Growth inhibition by Abl requires an interplay of its SH2 and tyrosine kinase domains.

Mattioni T, Mayer BJ, Picard D. Mattioni T, et al. Among authors: picard d. FEBS Lett. 1996 Jul 22;390(2):170-4. doi: 10.1016/0014-5793(96)00650-3. FEBS Lett. 1996. PMID: 8706852 Free article.

10

Functional analysis of the yeast 40 kDa cyclophilin Cyp40 and its role for viability and steroid receptor regulation.

Warth R, Briand PA, Picard D. Warth R, et al. Among authors: picard d. Biol Chem. 1997 May;378(5):381-91. doi: 10.1515/bchm.1997.378.5.381. Biol Chem. 1997. PMID: 9191025

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