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The podoplanin-CLEC-2 axis inhibits inflammation in sepsis.
Rayes J, Lax S, Wichaiyo S, Watson SK, Di Y, Lombard S, Grygielska B, Smith SW, Skordilis K, Watson SP. Rayes J, et al. Among authors: wichaiyo s. Nat Commun. 2017 Dec 21;8(1):2239. doi: 10.1038/s41467-017-02402-6. Nat Commun. 2017. PMID: 29269852 Free PMC article.
Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse.
Lax S, Rayes J, Wichaiyo S, Haining EJ, Lowe K, Grygielska B, Laloo R, Flodby P, Borok Z, Crandall ED, Thickett DR, Watson SP. Lax S, et al. Among authors: wichaiyo s. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1016-L1029. doi: 10.1152/ajplung.00023.2017. Epub 2017 Aug 24. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28839100 Free PMC article.
Lymphatic blood filling in CLEC-2-deficient mouse models.
Haining EJ, Lowe KL, Wichaiyo S, Kataru RP, Nagy Z, Kavanagh DP, Lax S, Di Y, Nieswandt B, Ho-Tin-Noé B, Mehrara BJ, Senis YA, Rayes J, Watson SP. Haining EJ, et al. Among authors: wichaiyo s. Platelets. 2021 Apr 3;32(3):352-367. doi: 10.1080/09537104.2020.1734784. Epub 2020 Mar 4. Platelets. 2021. PMID: 32129691 Free PMC article.
The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent.
Rayes J, Jadoui S, Lax S, Gros A, Wichaiyo S, Ollivier V, Denis CV, Ware J, Nieswandt B, Jandrot-Perrus M, Watson SP, Ho-Tin-Noé B. Rayes J, et al. Among authors: wichaiyo s. Haematologica. 2018 Jun;103(6):e256-e258. doi: 10.3324/haematol.2017.182162. Epub 2018 Feb 1. Haematologica. 2018. PMID: 29419432 Free PMC article. No abstract available.
21 results