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Conditional CRH overexpressing mice: an animal model for stress-elicited pathologies and treatments that target the central CRH system.
Lu A, Steiner MA, Whittle N, Vogl AM, Walser SM, Ableitner M, Refojo D, Ekker M, Rubenstein JL, Stalla GK, Singewald N, Holsboer F, Wotjak CT, Wurst W, Deussing JM. Lu A, et al. Among authors: deussing jm. Mol Psychiatry. 2008 Nov;13(11):989. doi: 10.1038/mp.2008.107. Mol Psychiatry. 2008. PMID: 18936754 No abstract available.
Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1.
Refojo D, Schweizer M, Kuehne C, Ehrenberg S, Thoeringer C, Vogl AM, Dedic N, Schumacher M, von Wolff G, Avrabos C, Touma C, Engblom D, Schütz G, Nave KA, Eder M, Wotjak CT, Sillaber I, Holsboer F, Wurst W, Deussing JM. Refojo D, et al. Among authors: deussing jm. Science. 2011 Sep 30;333(6051):1903-7. doi: 10.1126/science.1202107. Epub 2011 Sep 1. Science. 2011. PMID: 21885734
Consolidation of remote fear memories involves Corticotropin-Releasing Hormone (CRH) receptor type 1-mediated enhancement of AMPA receptor GluR1 signaling in the dentate gyrus.
Thoeringer CK, Henes K, Eder M, Dahlhoff M, Wurst W, Holsboer F, Deussing JM, Moosmang S, Wotjak CT. Thoeringer CK, et al. Among authors: deussing jm. Neuropsychopharmacology. 2012 Feb;37(3):787-96. doi: 10.1038/npp.2011.256. Epub 2011 Oct 26. Neuropsychopharmacology. 2012. PMID: 22030710 Free PMC article.
Fkbp52 heterozygosity alters behavioral, endocrine and neurogenetic parameters under basal and chronic stress conditions in mice.
Hartmann J, Wagner KV, Dedic N, Marinescu D, Scharf SH, Wang XD, Deussing JM, Hausch F, Rein T, Schmidt U, Holsboer F, Müller MB, Schmidt MV. Hartmann J, et al. Among authors: deussing jm. Psychoneuroendocrinology. 2012 Dec;37(12):2009-21. doi: 10.1016/j.psyneuen.2012.04.017. Epub 2012 May 27. Psychoneuroendocrinology. 2012. PMID: 22641006
Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels.
Kratzer S, Mattusch C, Metzger MW, Dedic N, Noll-Hussong M, Kafitz KW, Eder M, Deussing JM, Holsboer F, Kochs E, Rammes G. Kratzer S, et al. Among authors: deussing jm. Front Cell Neurosci. 2013 Jul 19;7:91. doi: 10.3389/fncel.2013.00091. eCollection 2013. Front Cell Neurosci. 2013. PMID: 23882180 Free PMC article.
168 results