Savira F - Search Results

1

Inhibition of Apoptosis Signal-Regulating Kinase 1 Attenuates Myocyte Hypertrophy and Fibroblast Collagen Synthesis.

Yang W, Wang BH, Wang I, Huang L, Savira F, Kompa A, Jucker BM, Willette RN, Kelly D, Krum H, Li Z, Fu Q. Yang W, et al. Among authors: savira f. Heart Lung Circ. 2019 Mar;28(3):495-504. doi: 10.1016/j.hlc.2017.12.001. Epub 2017 Dec 14. Heart Lung Circ. 2019. PMID: 29277546

2

Apoptosis signal-regulating kinase 1 inhibition attenuates cardiac hypertrophy and cardiorenal fibrosis induced by uremic toxins: Implications for cardiorenal syndrome.

Savira F, Cao L, Wang I, Yang W, Huang K, Hua Y, Jucker BM, Willette RN, Huang L, Krum H, Li Z, Fu Q, Wang BH. Savira F, et al. PLoS One. 2017 Nov 6;12(11):e0187459. doi: 10.1371/journal.pone.0187459. eCollection 2017. PLoS One. 2017. PMID: 29107962 Free PMC article.

3

Inhibition of apoptosis signal-regulating kinase 1 ameliorates left ventricular dysfunction by reducing hypertrophy and fibrosis in a rat model of cardiorenal syndrome.

Savira F, Wang BH, Edgley AJ, Jucker BM, Willette RN, Krum H, Kelly DJ, Kompa AR. Savira F, et al. Int J Cardiol. 2020 Jul 1;310:128-136. doi: 10.1016/j.ijcard.2020.04.015. Epub 2020 Apr 6. Int J Cardiol. 2020. PMID: 32305147

4

RE: Inhibition of apoptosis signal-regulating kinase 1 might be a novel therapeutic target in the treatment of cardiorenal syndrome.

Savira F, Edgley AJ, Jucker BM, Willette RN, Krum H, Kelly DJ, Kompa AR, Wang BH. Savira F, et al. Int J Cardiol. 2021 Jan 15;323:260. doi: 10.1016/j.ijcard.2020.09.021. Epub 2020 Sep 10. Int J Cardiol. 2021. PMID: 32920075 No abstract available.

5

Apoptosis signal-regulating kinase 1 inhibition reverses deleterious indoxyl sulfate-mediated endothelial effects.

Savira F, Kompa AR, Magaye R, Xiong X, Huang L, Jucker BM, Willette RN, Kelly DJ, Wang BH. Savira F, et al. Life Sci. 2021 May 1;272:119267. doi: 10.1016/j.lfs.2021.119267. Epub 2021 Feb 22. Life Sci. 2021. PMID: 33631173

6

Exogenous dihydrosphingosine 1 phosphate mediates collagen synthesis in cardiac fibroblasts through JAK/STAT signalling and regulation of TIMP1.

Magaye RR, Savira F, Hua Y, Xiong X, Huang L, Reid C, Flynn B, Kaye D, Liew D, Wang BH. Magaye RR, et al. Among authors: savira f. Cell Signal. 2020 Aug;72:109629. doi: 10.1016/j.cellsig.2020.109629. Epub 2020 Apr 8. Cell Signal. 2020. PMID: 32278008

7

RE: ASK1, a new target in treating cardiorenal syndrome (CRS).

Savira F, Kompa AR, Edgley AJ, Jucker BM, Willette RN, Kelly DJ, Wang BH. Savira F, et al. Int J Cardiol. 2020 Oct 1;316:207. doi: 10.1016/j.ijcard.2020.05.050. Int J Cardiol. 2020. PMID: 32891263 No abstract available.

8

RE: Blockade of apoptosis signal-regulating kinase 1 ameliorates cardiac dysfunction in cardiorenal syndrome via enhancing angiogenesis.

Savira F, Kompa AR, Edgley AJ, Jucker BM, Willette RN, Kelly DJ, Wang BH. Savira F, et al. Int J Cardiol. 2021 Mar 1;326:156. doi: 10.1016/j.ijcard.2020.10.035. Epub 2020 Oct 17. Int J Cardiol. 2021. PMID: 33080285 No abstract available.

9

Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells.

Magaye RR, Savira F, Hua Y, Xiong X, Huang L, Reid C, Flynn BL, Kaye D, Liew D, Wang BH. Magaye RR, et al. Among authors: savira f. Int J Biochem Cell Biol. 2021 May;134:105952. doi: 10.1016/j.biocel.2021.105952. Epub 2021 Feb 17. Int J Biochem Cell Biol. 2021. PMID: 33609744

10

Sphingolipid imbalance and inflammatory effects induced by uremic toxins in heart and kidney cells are reversed by dihydroceramide desaturase 1 inhibition.

Savira F, Magaye R, Scullino CV, Flynn BL, Pitson SM, Anderson D, Creek DJ, Hua Y, Xiong X, Huang L, Liew D, Reid C, Kaye D, Kompa AR, Wang BH. Savira F, et al. Toxicol Lett. 2021 Oct 10;350:133-142. doi: 10.1016/j.toxlet.2021.07.012. Epub 2021 Jul 22. Toxicol Lett. 2021. PMID: 34303789

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