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Reply to Pandey et al.: Understanding the efficacy of a potential antiretroviral drug candidate in humanized mouse model of HIV infection.
Kudalkar SN, Beloor J, Quijano E, Spasov KA, Lee WG, Cisneros JA, Saltzman WM, Kumar P, Jorgensen WL, Anderson KS. Kudalkar SN, et al. Among authors: cisneros ja. Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8114-E8115. doi: 10.1073/pnas.1810136115. Epub 2018 Aug 10. Proc Natl Acad Sci U S A. 2018. PMID: 30097540 Free PMC article. No abstract available.
Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV.
Kudalkar SN, Ullah I, Bertoletti N, Mandl HK, Cisneros JA, Beloor J, Chan AH, Quijano E, Saltzman WM, Jorgensen WL, Kumar P, Anderson KS. Kudalkar SN, et al. Among authors: cisneros ja. Antiviral Res. 2019 Jul;167:110-116. doi: 10.1016/j.antiviral.2019.04.010. Epub 2019 Apr 26. Antiviral Res. 2019. PMID: 31034849 Free PMC article.
Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead.
Ippolito JA, Niu H, Bertoletti N, Carter ZJ, Jin S, Spasov KA, Cisneros JA, Valhondo M, Cutrona KJ, Anderson KS, Jorgensen WL. Ippolito JA, et al. Among authors: cisneros ja. ACS Med Chem Lett. 2021 Jan 6;12(2):249-255. doi: 10.1021/acsmedchemlett.0c00612. eCollection 2021 Feb 11. ACS Med Chem Lett. 2021. PMID: 33603971 Free PMC article.
A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium.
Mukerjee A, Iyidogan P, Castellanos-Gonzalez A, Cisneros JA, Czyzyk D, Ranjan AP, Jorgensen WL, White AC Jr, Vishwanatha JK, Anderson KS. Mukerjee A, et al. Among authors: cisneros ja. Bioorg Med Chem Lett. 2015;25(10):2065-7. doi: 10.1016/j.bmcl.2015.03.091. Epub 2015 Apr 4. Bioorg Med Chem Lett. 2015. PMID: 25900220 Free PMC article.
Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase.
Kumar VP, Cisneros JA, Frey KM, Castellanos-Gonzalez A, Wang Y, Gangjee A, White AC Jr, Jorgensen WL, Anderson KS. Kumar VP, et al. Among authors: cisneros ja. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4158-61. doi: 10.1016/j.bmcl.2014.07.049. Epub 2014 Jul 24. Bioorg Med Chem Lett. 2014. PMID: 25127103 Free PMC article.
49 results