Georg GI - Search Results

1

Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception.

Syeda SS, Sánchez G, Hong KH, Hawkinson JE, Georg GI, Blanco G. Syeda SS, et al. Among authors: georg gi. J Med Chem. 2018 Mar 8;61(5):1800-1820. doi: 10.1021/acs.jmedchem.7b00925. Epub 2018 Jan 19. J Med Chem. 2018. PMID: 29291372 Free PMC article.

2

Synthesis of biologically active taxol analogues with modified phenylisoserine side chains.

Georg GI, Cheruvallath ZS, Himes RH, Mejillano MR, Burke CT. Georg GI, et al. J Med Chem. 1992 Oct 30;35(22):4230-7. doi: 10.1021/jm00100a031. J Med Chem. 1992. PMID: 1359143

3

Novel cytotoxic 3'-(tert-butyl) 3'-dephenyl analogs of paclitaxel and docetaxel.

Ali SM, Hoemann MZ, Aubé J, Mitscher LA, Georg GI, McCall R, Jayasinghe LR. Ali SM, et al. Among authors: georg gi. J Med Chem. 1995 Sep 15;38(19):3821-8. doi: 10.1021/jm00019a012. J Med Chem. 1995. PMID: 7562913

4

The effect of the aromatic rings of taxol on biological activity and solution conformation: synthesis and evaluation of saturated taxol and taxotere analogues.

Boge TC, Himes RH, Vander Velde DG, Georg GI. Boge TC, et al. Among authors: georg gi. J Med Chem. 1994 Sep 30;37(20):3337-43. doi: 10.1021/jm00046a018. J Med Chem. 1994. PMID: 7932561

5

4-Deacetyltaxol and 10-acetyl-4-deacetyltaxotere: synthesis and biological evaluation.

Datta A, Jayasinghe LR, Georg GI. Datta A, et al. Among authors: georg gi. J Med Chem. 1994 Nov 25;37(24):4258-60. doi: 10.1021/jm00050a023. J Med Chem. 1994. PMID: 7990125

6

Preparation of phenolic paclitaxel metabolites.

Park H, Hepperle M, Boge TC, Himes RH, Georg GI. Park H, et al. Among authors: georg gi. J Med Chem. 1996 Jul 5;39(14):2705-9. doi: 10.1021/jm960142x. J Med Chem. 1996. PMID: 8709100

7

Butitaxel analogues: synthesis and structure-activity relationships.

Ali SM, Hoemann MZ, Aubé J, Georg GI, Mitscher LA, Jayasinghe LR. Ali SM, et al. Among authors: georg gi. J Med Chem. 1997 Jan 17;40(2):236-41. doi: 10.1021/jm960505t. J Med Chem. 1997. PMID: 9003522

8

Halohydrin analogues of cryptophycin 1: synthesis and biological activity.

Georg GI, Ali SM, Stella VJ, Waugh WN, Himes RH. Georg GI, et al. Bioorg Med Chem Lett. 1998 Aug 4;8(15):1959-62. doi: 10.1016/s0960-894x(98)00356-4. Bioorg Med Chem Lett. 1998. PMID: 9873466

9

Enantioselective synthesis of a 3'-dephenylcryptophycin synthon.

Eggen MJ, Georg GI. Eggen MJ, et al. Among authors: georg gi. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3177-80. doi: 10.1016/s0960-894x(98)00557-5. Bioorg Med Chem Lett. 1998. PMID: 9873698

10

Synthesis and evaluation of paclitaxel C7 derivatives: solution phase synthesis of combinatorial libraries.

Bhat L, Liu Y, Victory SF, Himes RH, Georg GI. Bhat L, et al. Among authors: georg gi. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3181-6. doi: 10.1016/s0960-894x(98)00551-4. Bioorg Med Chem Lett. 1998. PMID: 9873699

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