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Page 1
Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4-1BB).
Azpilikueta A, Bolaños E, Lang V, Labiano S, Aznar MA, Etxeberria I, Teijeira A, Rodriguez-Ruiz ME, Perez-Gracia JL, Jure-Kunkel M, Zapata JM, Rodriguez MS, Melero I. Azpilikueta A, et al. Among authors: aznar ma. Oncoimmunology. 2017 Sep 21;7(1):e1368605. doi: 10.1080/2162402X.2017.1368605. eCollection 2017. Oncoimmunology. 2017. PMID: 29296520 Free PMC article.
Mitochondrial Morphological and Functional Reprogramming Following CD137 (4-1BB) Costimulation.
Teijeira A, Labiano S, Garasa S, Etxeberria I, Santamaría E, Rouzaut A, Enamorado M, Azpilikueta A, Inoges S, Bolaños E, Aznar MA, Sánchez-Paulete AR, Sancho D, Melero I. Teijeira A, et al. Among authors: aznar ma. Cancer Immunol Res. 2018 Jul;6(7):798-811. doi: 10.1158/2326-6066.CIR-17-0767. Epub 2018 Apr 20. Cancer Immunol Res. 2018. PMID: 29678874
Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells.
Sánchez-Paulete AR, Cueto FJ, Martínez-López M, Labiano S, Morales-Kastresana A, Rodríguez-Ruiz ME, Jure-Kunkel M, Azpilikueta A, Aznar MA, Quetglas JI, Sancho D, Melero I. Sánchez-Paulete AR, et al. Among authors: aznar ma. Cancer Discov. 2016 Jan;6(1):71-9. doi: 10.1158/2159-8290.CD-15-0510. Epub 2015 Oct 22. Cancer Discov. 2016. PMID: 26493961 Free PMC article.
Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism.
Labiano S, Palazón A, Bolaños E, Azpilikueta A, Sánchez-Paulete AR, Morales-Kastresana A, Quetglas JI, Perez-Gracia JL, Gúrpide A, Rodriguez-Ruiz M, Aznar MA, Jure-Kunkel M, Berraondo P, Melero I. Labiano S, et al. Among authors: aznar ma. Oncoimmunology. 2015 Jun 24;5(1):e1062967. doi: 10.1080/2162402X.2015.1062967. eCollection 2016. Oncoimmunology. 2015. PMID: 26942078 Free PMC article.
Abscopal Effects of Radiotherapy Are Enhanced by Combined Immunostimulatory mAbs and Are Dependent on CD8 T Cells and Crosspriming.
Rodriguez-Ruiz ME, Rodriguez I, Garasa S, Barbes B, Solorzano JL, Perez-Gracia JL, Labiano S, Sanmamed MF, Azpilikueta A, Bolaños E, Sanchez-Paulete AR, Aznar MA, Rouzaut A, Schalper KA, Jure-Kunkel M, Melero I. Rodriguez-Ruiz ME, et al. Among authors: aznar ma. Cancer Res. 2016 Oct 15;76(20):5994-6005. doi: 10.1158/0008-5472.CAN-16-0549. Epub 2016 Aug 22. Cancer Res. 2016. PMID: 27550452
CD69 is a direct HIF-1α target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes.
Labiano S, Meléndez-Rodríguez F, Palazón A, Teijeira Á, Garasa S, Etxeberria I, Aznar MÁ, Sánchez-Paulete AR, Azpilikueta A, Bolaños E, Molina C, de la Fuente H, Maiso P, Sánchez-Madrid F, de Landázuri MO, Aragonés J, Melero I. Labiano S, et al. Among authors: aznar ma. Oncoimmunology. 2017 Jan 19;6(4):e1283468. doi: 10.1080/2162402X.2017.1283468. eCollection 2017. Oncoimmunology. 2017. PMID: 28507790 Free PMC article.
CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8+ T Cell-Relevant Genes.
Aznar MA, Labiano S, Diaz-Lagares A, Molina C, Garasa S, Azpilikueta A, Etxeberria I, Sanchez-Paulete AR, Korman AJ, Esteller M, Sandoval J, Melero I. Aznar MA, et al. Cancer Immunol Res. 2018 Jan;6(1):69-78. doi: 10.1158/2326-6066.CIR-17-0159. Epub 2017 Nov 13. Cancer Immunol Res. 2018. PMID: 29133290
Repurposing the yellow fever vaccine for intratumoral immunotherapy.
Aznar MA, Molina C, Teijeira A, Rodriguez I, Azpilikueta A, Garasa S, Sanchez-Paulete AR, Cordeiro L, Etxeberria I, Alvarez M, Rius-Rocabert S, Nistal-Villan E, Berraondo P, Melero I. Aznar MA, et al. EMBO Mol Med. 2020 Jan 9;12(1):e10375. doi: 10.15252/emmm.201910375. Epub 2019 Nov 19. EMBO Mol Med. 2020. PMID: 31746149 Free PMC article.
Cytokines in clinical cancer immunotherapy.
Berraondo P, Sanmamed MF, Ochoa MC, Etxeberria I, Aznar MA, Pérez-Gracia JL, Rodríguez-Ruiz ME, Ponz-Sarvise M, Castañón E, Melero I. Berraondo P, et al. Among authors: aznar ma. Br J Cancer. 2019 Jan;120(1):6-15. doi: 10.1038/s41416-018-0328-y. Epub 2018 Nov 9. Br J Cancer. 2019. PMID: 30413827 Free PMC article. Review.
40 results