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F-box proteins in epigenetic regulation of cancer.
Shen J, Spruck C. Shen J, et al. Oncotarget. 2017 Nov 16;8(66):110650-110655. doi: 10.18632/oncotarget.22469. eCollection 2017 Dec 15. Oncotarget. 2017. PMID: 29299176 Free PMC article. Review.
Targeting FBXO44/SUV39H1 elicits tumor cell-specific DNA replication stress and viral mimicry.
Shen JZ, Spruck C. Shen JZ, et al. Cell Stress. 2021 Feb 18;5(3):37-39. doi: 10.15698/cst2021.03.245. Cell Stress. 2021. PMID: 33681705 Free PMC article.
Therefore, uncovering cancer cell-specific RE silencing mechanisms could provide a basis for the development of a new generation of cancer immunotherapy drugs. In our study (Shen et al. (2020), Cell, doi: 10.1016/j.cell.2020.11.042), through a high-content RNAi scre …
Therefore, uncovering cancer cell-specific RE silencing mechanisms could provide a basis for the development of a new generation of cancer i …
Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells.
Qiu Z, Zhao L, Shen JZ, Liang Z, Wu Q, Yang K, Min L, Gimple RC, Yang Q, Bhargava S, Jin C, Kim C, Hinz D, Dixit D, Bernatchez JA, Prager BC, Zhang G, Dong Z, Lv D, Wang X, Kim LJY, Zhu Z, Jones KA, Zheng Y, Wang X, Siqueira-Neto JL, Chavez L, Fu XD, Spruck C, Rich JN. Qiu Z, et al. Among authors: shen jz. Cancer Discov. 2022 Feb;12(2):502-521. doi: 10.1158/2159-8290.CD-20-1848. Epub 2021 Oct 6. Cancer Discov. 2022. PMID: 34615656 Free PMC article.
A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells.
Shen JZ, Qiu Z, Wu Q, Zhang G, Harris R, Sun D, Rantala J, Barshop WD, Zhao L, Lv D, Won KA, Wohlschlegel J, Sangfelt O, Laman H, Rich JN, Spruck C. Shen JZ, et al. Mol Cell. 2022 Mar 17;82(6):1123-1139.e8. doi: 10.1016/j.molcel.2022.01.022. Epub 2022 Feb 18. Mol Cell. 2022. Retraction in: Mol Cell. 2024 Jun 20;84(12):2398. doi: 10.1016/j.molcel.2024.05.022. PMID: 35182481 Free PMC article. Retracted.
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