Khleif SN - Search Results

1

Antigen-Specific Antitumor Responses Induced by OX40 Agonist Are Enhanced by the IDO Inhibitor Indoximod.

Berrong Z, Mkrtichyan M, Ahmad S, Webb M, Mohamed E, Okoev G, Matevosyan A, Shrimali R, Abu Eid R, Hammond S, Janik JE, Khleif SN. Berrong Z, et al. Among authors: khleif sn. Cancer Immunol Res. 2018 Feb;6(2):201-208. doi: 10.1158/2326-6066.CIR-17-0223. Epub 2018 Jan 5. Cancer Immunol Res. 2018. PMID: 29305519

2

Selective inhibition of regulatory T cells by targeting the PI3K-Akt pathway.

Abu-Eid R, Samara RN, Ozbun L, Abdalla MY, Berzofsky JA, Friedman KM, Mkrtichyan M, Khleif SN. Abu-Eid R, et al. Among authors: khleif sn. Cancer Immunol Res. 2014 Nov;2(11):1080-9. doi: 10.1158/2326-6066.CIR-14-0095. Epub 2014 Jul 30. Cancer Immunol Res. 2014. PMID: 25080445 Free PMC article.

3

Mutant KRAS Conversion of Conventional T Cells into Regulatory T Cells.

Zdanov S, Mandapathil M, Abu Eid R, Adamson-Fadeyi S, Wilson W, Qian J, Carnie A, Tarasova N, Mkrtichyan M, Berzofsky JA, Whiteside TL, Khleif SN. Zdanov S, et al. Among authors: khleif sn. Cancer Immunol Res. 2016 Apr;4(4):354-65. doi: 10.1158/2326-6066.CIR-15-0241. Epub 2016 Feb 15. Cancer Immunol Res. 2016. PMID: 26880715 Free PMC article.

4

Old-School Chemotherapy in Immunotherapeutic Combination in Cancer, A Low-cost Drug Repurposed.

Abu Eid R, Razavi GS, Mkrtichyan M, Janik J, Khleif SN. Abu Eid R, et al. Among authors: khleif sn. Cancer Immunol Res. 2016 May;4(5):377-82. doi: 10.1158/2326-6066.CIR-16-0048. Epub 2016 May 1. Cancer Immunol Res. 2016. PMID: 27196429 Review.

5

Differential PI3Kδ Signaling in CD4⁺ T-cell Subsets Enables Selective Targeting of T Regulatory Cells to Enhance Cancer Immunotherapy.

Ahmad S, Abu-Eid R, Shrimali R, Webb M, Verma V, Doroodchi A, Berrong Z, Samara R, Rodriguez PC, Mkrtichyan M, Khleif SN. Ahmad S, et al. Among authors: khleif sn. Cancer Res. 2017 Apr 15;77(8):1892-1904. doi: 10.1158/0008-5472.CAN-16-1839. Epub 2017 Jan 20. Cancer Res. 2017. PMID: 28108509

6

Enhanced Therapeutic Efficacy and Memory of Tumor-Specific CD8 T Cells by Ex Vivo PI3K-δ Inhibition.

Abu Eid R, Ahmad S, Lin Y, Webb M, Berrong Z, Shrimali R, Kumai T, Ananth S, Rodriguez PC, Celis E, Janik J, Mkrtichyan M, Khleif SN. Abu Eid R, et al. Among authors: khleif sn. Cancer Res. 2017 Aug 1;77(15):4135-4145. doi: 10.1158/0008-5472.CAN-16-1925. Epub 2017 Jun 14. Cancer Res. 2017. PMID: 28615225

7

Agonist anti-GITR antibody significantly enhances the therapeutic efficacy of Listeria monocytogenes-based immunotherapy.

Shrimali R, Ahmad S, Berrong Z, Okoev G, Matevosyan A, Razavi GSE, Petit R, Gupta S, Mkrtichyan M, Khleif SN. Shrimali R, et al. Among authors: khleif sn. J Immunother Cancer. 2017 Aug 15;5(1):64. doi: 10.1186/s40425-017-0266-x. J Immunother Cancer. 2017. PMID: 28807056 Free PMC article.

8

Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-cell Apoptosis.

Shrimali RK, Ahmad S, Verma V, Zeng P, Ananth S, Gaur P, Gittelman RM, Yusko E, Sanders C, Robins H, Hammond SA, Janik JE, Mkrtichyan M, Gupta S, Khleif SN. Shrimali RK, et al. Among authors: khleif sn. Cancer Immunol Res. 2017 Sep;5(9):755-766. doi: 10.1158/2326-6066.CIR-17-0292. Cancer Immunol Res. 2017. PMID: 28848055

9

Anti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy.

Mkrtichyan M, Chong N, Abu Eid R, Wallecha A, Singh R, Rothman J, Khleif SN. Mkrtichyan M, et al. Among authors: khleif sn. J Immunother Cancer. 2013 Aug 29;1:15. doi: 10.1186/2051-1426-1-15. eCollection 2013. J Immunother Cancer. 2013. PMID: 24829751 Free PMC article.

10

Programmed death-1 & its ligands: promising targets for cancer immunotherapy.

Shrimali RK, Janik JE, Abu-Eid R, Mkrtichyan M, Khleif SN. Shrimali RK, et al. Among authors: khleif sn. Immunotherapy. 2015;7(7):777-92. doi: 10.2217/imt.15.49. Epub 2015 Aug 7. Immunotherapy. 2015. PMID: 26250412 Review.

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