Parsons SM - Search Results

1

Kinetic modeling of [¹⁸ F]VAT, a novel radioligand for positron emission tomography imaging vesicular acetylcholine transporter in non-human primate brain.

Jin H, Yue X, Liu H, Han J, Flores H, Su Y, Parsons SM, Perlmutter JS, Tu Z. Jin H, et al. Among authors: parsons sm. J Neurochem. 2018 Mar;144(6):791-804. doi: 10.1111/jnc.14291. Epub 2018 Mar 25. J Neurochem. 2018. PMID: 29315563 Free PMC article.

2

In vitro and ex vivo characterization of (-)-TZ659 as a ligand for imaging the vesicular acetylcholine transporter.

Liu H, Jin H, Li J, Zhang X, Kaneshige K, Parsons SM, Perlmutter JS, Tu Z. Liu H, et al. Among authors: parsons sm. Eur J Pharmacol. 2015 Apr 5;752:18-25. doi: 10.1016/j.ejphar.2015.02.001. Epub 2015 Feb 9. Eur J Pharmacol. 2015. PMID: 25678250 Free PMC article.

3

Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter.

Tu Z, Zhang X, Jin H, Yue X, Padakanti PK, Yu L, Liu H, Flores HP, Kaneshige K, Parsons SM, Perlmutter JS. Tu Z, et al. Among authors: parsons sm. Bioorg Med Chem. 2015 Aug 1;23(15):4699-4709. doi: 10.1016/j.bmc.2015.05.058. Epub 2015 Jun 5. Bioorg Med Chem. 2015. PMID: 26138195 Free PMC article.

4

Kinetics modeling and occupancy studies of a novel C-11 PET tracer for VAChT in nonhuman primates.

Jin H, Zhang X, Yue X, Liu H, Li J, Yang H, Flores H, Su Y, Parsons SM, Perlmutter JS, Tu Z. Jin H, et al. Among authors: parsons sm. Nucl Med Biol. 2016 Feb;43(2):131-9. doi: 10.1016/j.nucmedbio.2015.11.003. Epub 2015 Nov 7. Nucl Med Biol. 2016. PMID: 26872437 Free PMC article.

5

Chiral resolution of serial potent and selective σ₁ ligands and biological evaluation of (-)-[¹⁸F]TZ3108 in rodent and the nonhuman primate brain.

Yue X, Jin H, Luo Z, Liu H, Zhang X, McSpadden ED, Tian L, Flores HP, Perlmutter JS, Parsons SM, Tu Z. Yue X, et al. Among authors: parsons sm. Bioorg Med Chem. 2017 Feb 15;25(4):1533-1542. doi: 10.1016/j.bmc.2017.01.017. Epub 2017 Jan 16. Bioorg Med Chem. 2017. PMID: 28129990 Free PMC article.

6

Synthesis, resolution, and in vitro evaluation of three vesicular acetylcholine transporter ligands and evaluation of the lead fluorine-18 radioligand in a nonhuman primate.

Yue X, Jin H, Liu H, Luo Z, Zhang X, Kaneshige K, Flores HP, Perlmutter JS, Parsons SM, Tu Z. Yue X, et al. Among authors: parsons sm. Org Biomol Chem. 2017 Jun 21;15(24):5197-5209. doi: 10.1039/c7ob00854f. Org Biomol Chem. 2017. PMID: 28590490 Free PMC article.

7

Exploration of Sulfur-Containing Analogues for Imaging Vesicular Acetylcholine Transporter in the Brain.

Luo Z, Liu H, Jin H, Gu J, Yu Y, Kaneshige K, Perlmutter JS, Parsons SM, Tu Z. Luo Z, et al. Among authors: parsons sm. ChemMedChem. 2018 Sep 19;13(18):1978-1987. doi: 10.1002/cmdc.201800411. Epub 2018 Aug 19. ChemMedChem. 2018. PMID: 30071131 Free PMC article.

8

Radiosynthesis and evaluation of a fluorine-18 labeled radioligand targeting vesicular acetylcholine transporter.

Yue X, Luo Z, Liu H, Kaneshige K, Parsons SM, Perlmutter JS, Tu Z. Yue X, et al. Among authors: parsons sm. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3425-3430. doi: 10.1016/j.bmcl.2018.09.030. Epub 2018 Sep 24. Bioorg Med Chem Lett. 2018. PMID: 30274694 Free PMC article.

9

The impact of dopamine D₂-like agonist/antagonist on [¹⁸F]VAT PET measurement of VAChT in the brain of nonhuman primates.

Liu H, Luo Z, Gu J, Su Y, Flores H, Parsons SM, Zhou Y, Perlmutter JS, Tu Z. Liu H, et al. Among authors: parsons sm. Eur J Pharm Sci. 2020 Feb 15;143:105152. doi: 10.1016/j.ejps.2019.105152. Epub 2019 Nov 15. Eur J Pharm Sci. 2020. PMID: 31740395 Free PMC article.

10

Heteroaromatic and aniline derivatives of piperidines as potent ligands for vesicular acetylcholine transporter.

Li J, Zhang X, Zhang Z, Padakanti PK, Jin H, Cui J, Li A, Zeng D, Rath NP, Flores H, Perlmutter JS, Parsons SM, Tu Z. Li J, et al. Among authors: parsons sm. J Med Chem. 2013 Aug 8;56(15):6216-33. doi: 10.1021/jm400664x. Epub 2013 Jul 18. J Med Chem. 2013. PMID: 23802889 Free PMC article.

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