Liu J - Search Results

1

Partial rescue of F508del-cystic fibrosis transmembrane conductance regulator channel gating with modest improvement of protein processing, but not stability, by a dual-acting small molecule.

Liu J, Bihler H, Farinha CM, Awatade NT, Romão AM, Mercadante D, Cheng Y, Musisi I, Jantarajit W, Wang Y, Cai Z, Amaral MD, Mense M, Sheppard DN. Liu J, et al. Br J Pharmacol. 2018 Apr;175(7):1017-1038. doi: 10.1111/bph.14141. Epub 2018 Feb 22. Br J Pharmacol. 2018. PMID: 29318594 Free PMC article.

2

Targeting F508del-CFTR to develop rational new therapies for cystic fibrosis.

Cai ZW, Liu J, Li HY, Sheppard DN. Cai ZW, et al. Among authors: liu j. Acta Pharmacol Sin. 2011 Jun;32(6):693-701. doi: 10.1038/aps.2011.71. Acta Pharmacol Sin. 2011. PMID: 21642944 Free PMC article. Review.

3

Loop diuretics are open-channel blockers of the cystic fibrosis transmembrane conductance regulator with distinct kinetics.

Ju M, Scott-Ward TS, Liu J, Khuituan P, Li H, Cai Z, Husbands SM, Sheppard DN. Ju M, et al. Among authors: liu j. Br J Pharmacol. 2014 Jan;171(1):265-78. doi: 10.1111/bph.12458. Br J Pharmacol. 2014. PMID: 24117047 Free PMC article.

4

Revertant mutants modify, but do not rescue, the gating defect of the cystic fibrosis mutant G551D-CFTR.

Xu Z, Pissarra LS, Farinha CM, Liu J, Cai Z, Thibodeau PH, Amaral MD, Sheppard DN. Xu Z, et al. Among authors: liu j. J Physiol. 2014 May 1;592(9):1931-47. doi: 10.1113/jphysiol.2014.271817. Epub 2014 Mar 3. J Physiol. 2014. PMID: 24591578 Free PMC article.

5

CFTR potentiators partially restore channel function to A561E-CFTR, a cystic fibrosis mutant with a similar mechanism of dysfunction as F508del-CFTR.

Wang Y, Liu J, Loizidou A, Bugeja LA, Warner R, Hawley BR, Cai Z, Toye AM, Sheppard DN, Li H. Wang Y, et al. Among authors: liu j. Br J Pharmacol. 2014 Oct;171(19):4490-503. doi: 10.1111/bph.12791. Epub 2014 Sep 5. Br J Pharmacol. 2014. PMID: 24902474 Free PMC article.

6

Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR.

Bose SJ, Bijvelds MJC, Wang Y, Liu J, Cai Z, Bot AGM, de Jonge HR, Sheppard DN. Bose SJ, et al. Among authors: liu j. Am J Physiol Lung Cell Mol Physiol. 2019 Jul 1;317(1):L71-L86. doi: 10.1152/ajplung.00034.2019. Epub 2019 Apr 10. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30969810 Free PMC article.

7

Carbon monoxide-releasing molecules inhibit the cystic fibrosis transmembrane conductance regulator Cl^- channel.

Rodrat M, Jantarajit W, Ng DRS, Harvey BSJ, Liu J, Wilkinson WJ, Charoenphandhu N, Sheppard DN. Rodrat M, et al. Among authors: liu j. Am J Physiol Lung Cell Mol Physiol. 2020 Dec 1;319(6):L997-L1009. doi: 10.1152/ajplung.00440.2019. Epub 2020 Sep 16. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32936026 Free article.

8

A small molecule CFTR potentiator restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR.

Liu J, Berg AP, Wang Y, Jantarajit W, Sutcliffe KJ, Stevens EB, Cao L, Pregel MJ, Sheppard DN. Liu J, et al. Br J Pharmacol. 2022 Apr;179(7):1319-1337. doi: 10.1111/bph.15709. Epub 2022 Jan 21. Br J Pharmacol. 2022. PMID: 34644413 Free PMC article.

9

GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K_2P ) channel opener, reduces rat dorsal root ganglion neuron excitability.

Loucif AJC, Saintot PP, Liu J, Antonio BM, Zellmer SG, Yoger K, Veale EL, Wilbrey A, Omoto K, Cao L, Gutteridge A, Castle NA, Stevens EB, Mathie A. Loucif AJC, et al. Among authors: liu j. Br J Pharmacol. 2018 Jun;175(12):2272-2283. doi: 10.1111/bph.14098. Epub 2017 Dec 29. Br J Pharmacol. 2018. PMID: 29150838 Free PMC article.

10

AMP-dependent protein kinase alpha 1 predicts cancer prognosis and immunotherapy response: from pan-cancer analysis to experimental validation.

Yong T, Wei QY, Liu J, Wang YP, Huang WP, Lu Y, Wang C, Fan Y. Yong T, et al. Am J Cancer Res. 2024 Oct 25;14(10):5079-5094. doi: 10.62347/TIUW1528. eCollection 2024. Am J Cancer Res. 2024. PMID: 39553228 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

144,091 results

Search Page

Filters