Mély Y - Search Results

1

Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein.

Gamba E, Mori M, Kovalenko L, Giannini A, Sosic A, Saladini F, Fabris D, Mély Y, Gatto B, Botta M. Gamba E, et al. Among authors: mely y. Eur J Med Chem. 2018 Feb 10;145:154-164. doi: 10.1016/j.ejmech.2017.12.073. Epub 2017 Dec 24. Eur J Med Chem. 2018. PMID: 29324338 Free PMC article.

2

Destabilization of the HIV-1 complementary sequence of TAR by the nucleocapsid protein through activation of conformational fluctuations.

Azoulay J, Clamme JP, Darlix JL, Roques BP, Mély Y. Azoulay J, et al. Among authors: mely y. J Mol Biol. 2003 Feb 21;326(3):691-700. doi: 10.1016/s0022-2836(02)01430-4. J Mol Biol. 2003. PMID: 12581633

3

Investigation by fluorescence correlation spectroscopy of the chaperoning interactions of HIV-1 nucleocapsid protein with the viral DNA initiation sequences.

Egelé C, Schaub E, Piémont E, de Rocquigny H, Mély Y. Egelé C, et al. Among authors: mely y. C R Biol. 2005 Dec;328(12):1041-51. doi: 10.1016/j.crvi.2005.06.005. Epub 2005 Oct 24. C R Biol. 2005. PMID: 16314282 Free article.

4

A tryptophan-rich hexapeptide inhibits nucleic acid destabilization chaperoned by the HIV-1 nucleocapsid protein.

Raja C, Ferner J, Dietrich U, Avilov S, Ficheux D, Darlix JL, de Rocquigny H, Schwalbe H, Mély Y. Raja C, et al. Among authors: mely y. Biochemistry. 2006 Aug 1;45(30):9254-65. doi: 10.1021/bi052560m. Biochemistry. 2006. PMID: 16866372

5

Targeting the viral nucleocapsid protein in anti-HIV-1 therapy.

de Rocquigny H, Shvadchak V, Avilov S, Dong CZ, Dietrich U, Darlix JL, Mély Y. de Rocquigny H, et al. Among authors: mely y. Mini Rev Med Chem. 2008 Jan;8(1):24-35. doi: 10.2174/138955708783331603. Mini Rev Med Chem. 2008. PMID: 18220982 Review.

6

Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein.

Shvadchak V, Sanglier S, Rocle S, Villa P, Haiech J, Hibert M, Van Dorsselaer A, Mély Y, de Rocquigny H. Shvadchak V, et al. Among authors: mely y. Biochimie. 2009 Jul;91(7):916-23. doi: 10.1016/j.biochi.2009.04.014. Epub 2009 May 4. Biochimie. 2009. PMID: 19401213

7

Biophysical studies of the nucleic acid chaperone properties of the HIV-1 nucleocapsid protein.

Godet J, Mély Y. Godet J, et al. Among authors: mely y. RNA Biol. 2010 Nov-Dec;7(6):687-99. doi: 10.4161/rna.7.6.13616. Epub 2010 Nov 1. RNA Biol. 2010. PMID: 21045545 Free article. Review.

8

Characterization of the inhibition mechanism of HIV-1 nucleocapsid protein chaperone activities by methylated oligoribonucleotides.

Avilov SV, Boudier C, Gottikh M, Darlix JL, Mély Y. Avilov SV, et al. Among authors: mely y. Antimicrob Agents Chemother. 2012 Feb;56(2):1010-8. doi: 10.1128/AAC.05614-11. Epub 2011 Nov 14. Antimicrob Agents Chemother. 2012. PMID: 22083480 Free PMC article.

9

Use of virtual screening for discovering antiretroviral compounds interacting with the HIV-1 nucleocapsid protein.

Mori M, Schult-Dietrich P, Szafarowicz B, Humbert N, Debaene F, Sanglier-Cianferani S, Dietrich U, Mély Y, Botta M. Mori M, et al. Among authors: mely y. Virus Res. 2012 Nov;169(2):377-87. doi: 10.1016/j.virusres.2012.05.011. Epub 2012 May 24. Virus Res. 2012. PMID: 22634301 Review.

10

Two-color fluorescent l-amino acid mimic of tryptophan for probing peptide-nucleic acid complexes.

Strizhak AV, Postupalenko VY, Shvadchak VV, Morellet N, Guittet E, Pivovarenko VG, Klymchenko AS, Mély Y. Strizhak AV, et al. Among authors: mely y. Bioconjug Chem. 2012 Dec 19;23(12):2434-43. doi: 10.1021/bc300464u. Epub 2012 Nov 28. Bioconjug Chem. 2012. PMID: 23153224

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