Murphy M - Search Results

1

p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways.

Roy S, Tomaszowski KH, Luzwick JW, Park S, Li J, Murphy M, Schlacher K. Roy S, et al. Among authors: murphy m. Elife. 2018 Jan 15;7:e31723. doi: 10.7554/eLife.31723. Elife. 2018. PMID: 29334356 Free PMC article.

2

Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser.

Gnanapradeepan K, Leu JI, Basu S, Barnoud T, Good M, Lee JV, Quinn WJ, Kung CP, Ahima R, Baur JA, Wellen KE, Liu Q, Schug ZT, George DL, Murphy ME. Gnanapradeepan K, et al. Among authors: murphy me. Elife. 2020 Nov 10;9:e55994. doi: 10.7554/eLife.55994. Elife. 2020. PMID: 33170774 Free PMC article.

3

p53 differentially inhibits cell growth depending on the mechanism of telomere maintenance.

Razak ZR, Varkonyi RJ, Kulp-McEliece M, Caslini C, Testa JR, Murphy ME, Broccoli D. Razak ZR, et al. Among authors: murphy me. Mol Cell Biol. 2004 Jul;24(13):5967-77. doi: 10.1128/MCB.24.13.5967-5977.2004. Mol Cell Biol. 2004. PMID: 15199150 Free PMC article.

4

The codon 47 polymorphism in p53 is functionally significant.

Li X, Dumont P, Della Pietra A, Shetler C, Murphy ME. Li X, et al. J Biol Chem. 2005 Jun 24;280(25):24245-51. doi: 10.1074/jbc.M414637200. Epub 2005 Apr 25. J Biol Chem. 2005. PMID: 15851479 Free article.

5

Polymorphisms in the p53 pathway.

Pietsch EC, Humbey O, Murphy ME. Pietsch EC, et al. Among authors: murphy me. Oncogene. 2006 Mar 13;25(11):1602-11. doi: 10.1038/sj.onc.1209367. Oncogene. 2006. PMID: 16550160 Review.

6

The p53 family and programmed cell death.

Pietsch EC, Sykes SM, McMahon SB, Murphy ME. Pietsch EC, et al. Among authors: murphy me. Oncogene. 2008 Oct 27;27(50):6507-21. doi: 10.1038/onc.2008.315. Oncogene. 2008. PMID: 18955976 Free PMC article. Review.

7

Wild-type and mutant p53 proteins interact with mitochondrial caspase-3.

Frank AK, Pietsch EC, Dumont P, Tao J, Murphy ME. Frank AK, et al. Cancer Biol Ther. 2011 Apr 15;11(8):740-5. doi: 10.4161/cbt.11.8.14906. Epub 2011 Apr 15. Cancer Biol Ther. 2011. PMID: 21307660 Free PMC article.

8

Autophagy in tumor suppression and cancer therapy.

Kung CP, Budina A, Balaburski G, Bergenstock MK, Murphy M. Kung CP, et al. Among authors: murphy m. Crit Rev Eukaryot Gene Expr. 2011;21(1):71-100. doi: 10.1615/critreveukargeneexpr.v21.i1.50. Crit Rev Eukaryot Gene Expr. 2011. PMID: 21967333 Free PMC article. Review.

9

A conserved domain in exon 2 coding for the human and murine ARF tumor suppressor protein is required for autophagy induction.

Budina-Kolomets A, Hontz RD, Pimkina J, Murphy ME. Budina-Kolomets A, et al. Autophagy. 2013 Oct;9(10):1553-65. doi: 10.4161/auto.25831. Epub 2013 Aug 7. Autophagy. 2013. PMID: 23939042 Free PMC article.

10

Identification of TRIML2, a novel p53 target, that enhances p53 SUMOylation and regulates the transactivation of proapoptotic genes.

Kung CP, Khaku S, Jennis M, Zhou Y, Murphy ME. Kung CP, et al. Among authors: murphy me. Mol Cancer Res. 2015 Feb;13(2):250-62. doi: 10.1158/1541-7786.MCR-14-0385. Epub 2014 Sep 25. Mol Cancer Res. 2015. PMID: 25256710 Free PMC article.

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