Huang L - Search Results

1

Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations.

Huang L, Low A, Damle SS, Keenan MM, Kuntz S, Murray SF, Monia BP, Guo S. Huang L, et al. Genome Biol. 2018 Jan 15;19(1):4. doi: 10.1186/s13059-017-1386-9. Genome Biol. 2018. PMID: 29334995 Free PMC article.

2

CFTR mRNAs with nonsense codons are degraded by the SMG6-mediated endonucleolytic decay pathway.

Sanderlin EJ, Keenan MM, Mense M, Revenko AS, Monia BP, Guo S, Huang L. Sanderlin EJ, et al. Among authors: huang l. Nat Commun. 2022 Apr 29;13(1):2344. doi: 10.1038/s41467-022-29935-9. Nat Commun. 2022. PMID: 35487895 Free PMC article.

3

Nonsense-mediated RNA Decay Pathway Inhibition Restores Expression and Function of W1282X CFTR.

Keenan MM, Huang L, Jordan NJ, Wong E, Cheng Y, Valley HC, Mahiou J, Liang F, Bihler H, Mense M, Guo S, Monia BP. Keenan MM, et al. Among authors: huang l. Am J Respir Cell Mol Biol. 2019 Sep;61(3):290-300. doi: 10.1165/rcmb.2018-0316OC. Am J Respir Cell Mol Biol. 2019. PMID: 30836009

4

Targeting Translation Termination Machinery with Antisense Oligonucleotides for Diseases Caused by Nonsense Mutations.

Huang L, Aghajan M, Quesenberry T, Low A, Murray SF, Monia BP, Guo S. Huang L, et al. Nucleic Acid Ther. 2019 Aug;29(4):175-186. doi: 10.1089/nat.2019.0779. Epub 2019 May 9. Nucleic Acid Ther. 2019. PMID: 31070517 Free PMC article.

5

Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration.

Huang L, Damle SS, Booten S, Singh P, Sabripour M, Hsu J, Jo M, Katz M, Watt A, Hart CE, Freier SM, Monia BP, Guo S. Huang L, et al. PLoS One. 2015 Jul 24;10(7):e0132798. doi: 10.1371/journal.pone.0132798. eCollection 2015. PLoS One. 2015. PMID: 26207833 Free PMC article.

6

Knockdown of nuclear-retained long noncoding RNAs using modified DNA antisense oligonucleotides.

Zong X, Huang L, Tripathi V, Peralta R, Freier SM, Guo S, Prasanth KV. Zong X, et al. Among authors: huang l. Methods Mol Biol. 2015;1262:321-31. doi: 10.1007/978-1-4939-2253-6_20. Methods Mol Biol. 2015. PMID: 25555591

7

New approaches to genetic therapies for cystic fibrosis.

Christopher Boyd A, Guo S, Huang L, Kerem B, Oren YS, Walker AJ, Hart SL. Christopher Boyd A, et al. Among authors: huang l. J Cyst Fibros. 2020 Mar;19 Suppl 1:S54-S59. doi: 10.1016/j.jcf.2019.12.012. Epub 2020 Jan 13. J Cyst Fibros. 2020. PMID: 31948871 Free article. Review.

8

Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2.

Marín-Béjar O, Marchese FP, Athie A, Sánchez Y, González J, Segura V, Huang L, Moreno I, Navarro A, Monzó M, García-Foncillas J, Rinn JL, Guo S, Huarte M. Marín-Béjar O, et al. Among authors: huang l. Genome Biol. 2013;14(9):R104. doi: 10.1186/gb-2013-14-9-r104. Genome Biol. 2013. PMID: 24070194 Free PMC article.

9

Regulation of nonsense-mediated mRNA decay.

Huang L, Wilkinson MF. Huang L, et al. Wiley Interdiscip Rev RNA. 2012 Nov-Dec;3(6):807-28. doi: 10.1002/wrna.1137. Epub 2012 Oct 1. Wiley Interdiscip Rev RNA. 2012. PMID: 23027648 Review.

10

The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.

Shum EY, Jones SH, Shao A, Chousal JN, Krause MD, Chan WK, Lou CH, Espinoza JL, Song HW, Phan MH, Ramaiah M, Huang L, McCarrey JR, Peterson KJ, De Rooij DG, Cook-Andersen H, Wilkinson MF. Shum EY, et al. Among authors: huang l. Cell. 2016 Apr 7;165(2):382-95. doi: 10.1016/j.cell.2016.02.046. Epub 2016 Mar 31. Cell. 2016. PMID: 27040500 Free PMC article.

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