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Page 1
Phosphoinositide 3-Kinase Gamma Inhibition Protects From Anthracycline Cardiotoxicity and Reduces Tumor Growth.
Li M, Sala V, De Santis MC, Cimino J, Cappello P, Pianca N, Di Bona A, Margaria JP, Martini M, Lazzarini E, Pirozzi F, Rossi L, Franco I, Bornbaum J, Heger J, Rohrbach S, Perino A, Tocchetti CG, Lima BHF, Teixeira MM, Porporato PE, Schulz R, Angelini A, Sandri M, Ameri P, Sciarretta S, Lima-Júnior RCP, Mongillo M, Zaglia T, Morello F, Novelli F, Hirsch E, Ghigo A. Li M, et al. Among authors: porporato pe. Circulation. 2018 Aug 14;138(7):696-711. doi: 10.1161/CIRCULATIONAHA.117.030352. Circulation. 2018. PMID: 29348263 Free article.
Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting.
Wyart E, Reano S, Hsu MY, Longo DL, Li M, Hirsch E, Filigheddu N, Ghigo A, Riganti C, Porporato PE. Wyart E, et al. Among authors: porporato pe. Oxid Med Cell Longev. 2018 Feb 26;2018:6419805. doi: 10.1155/2018/6419805. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 29682162 Free PMC article.
Signaling Pathways Regulating Redox Balance in Cancer Metabolism.
De Santis MC, Porporato PE, Martini M, Morandi A. De Santis MC, et al. Among authors: porporato pe. Front Oncol. 2018 Apr 23;8:126. doi: 10.3389/fonc.2018.00126. eCollection 2018. Front Oncol. 2018. PMID: 29740540 Free PMC article. Review.
Metabolic Aspects of Anthracycline Cardiotoxicity.
Russo M, Della Sala A, Tocchetti CG, Porporato PE, Ghigo A. Russo M, et al. Among authors: porporato pe. Curr Treat Options Oncol. 2021 Feb 5;22(2):18. doi: 10.1007/s11864-020-00812-1. Curr Treat Options Oncol. 2021. PMID: 33547494 Free PMC article. Review.
Phosphoinositide Conversion Inactivates R-RAS and Drives Metastases in Breast Cancer.
Li H, Prever L, Hsu MY, Lo WT, Margaria JP, De Santis MC, Zanini C, Forni M, Novelli F, Pece S, Di Fiore PP, Porporato PE, Martini M, Belabed H, Nazare M, Haucke V, Gulluni F, Hirsch E. Li H, et al. Among authors: porporato pe. Adv Sci (Weinh). 2022 Mar;9(9):e2103249. doi: 10.1002/advs.202103249. Epub 2022 Jan 31. Adv Sci (Weinh). 2022. PMID: 35098698 Free PMC article.
Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia.
Wyart E, Hsu MY, Sartori R, Mina E, Rausch V, Pierobon ES, Mezzanotte M, Pezzini C, Bindels LB, Lauria A, Penna F, Hirsch E, Martini M, Mazzone M, Roetto A, Geninatti Crich S, Prenen H, Sandri M, Menga A, Porporato PE. Wyart E, et al. Among authors: porporato pe. EMBO Rep. 2022 Apr 5;23(4):e53746. doi: 10.15252/embr.202153746. Epub 2022 Feb 24. EMBO Rep. 2022. PMID: 35199910 Free PMC article.
Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer.
De Santis MC, Gozzelino L, Margaria JP, Costamagna A, Ratto E, Gulluni F, Di Gregorio E, Mina E, Lorito N, Bacci M, Lattanzio R, Sala G, Cappello P, Novelli F, Giovannetti E, Vicentini C, Andreani S, Delfino P, Corbo V, Scarpa A, Porporato PE, Morandi A, Hirsch E, Martini M. De Santis MC, et al. Among authors: porporato pe. Gut. 2023 Feb;72(2):360-371. doi: 10.1136/gutjnl-2021-325117. Epub 2022 May 27. Gut. 2023. PMID: 35623884 Free PMC article.
NAD+ repletion with niacin counteracts cancer cachexia.
Beltrà M, Pöllänen N, Fornelli C, Tonttila K, Hsu MY, Zampieri S, Moletta L, Corrà S, Porporato PE, Kivelä R, Viscomi C, Sandri M, Hulmi JJ, Sartori R, Pirinen E, Penna F. Beltrà M, et al. Among authors: porporato pe. Nat Commun. 2023 Apr 3;14(1):1849. doi: 10.1038/s41467-023-37595-6. Nat Commun. 2023. PMID: 37012289 Free PMC article.
Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells.
Filigheddu N, Gnocchi VF, Coscia M, Cappelli M, Porporato PE, Taulli R, Traini S, Baldanzi G, Chianale F, Cutrupi S, Arnoletti E, Ghè C, Fubini A, Surico N, Sinigaglia F, Ponzetto C, Muccioli G, Crepaldi T, Graziani A. Filigheddu N, et al. Among authors: porporato pe. Mol Biol Cell. 2007 Mar;18(3):986-94. doi: 10.1091/mbc.e06-05-0402. Epub 2007 Jan 3. Mol Biol Cell. 2007. PMID: 17202410 Free PMC article.
83 results