Gauss CM - Search Results

1

Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development.

Krishnan N, Bonham CA, Rus IA, Shrestha OK, Gauss CM, Haque A, Tocilj A, Joshua-Tor L, Tonks NK. Krishnan N, et al. Among authors: gauss cm. Nat Commun. 2018 Jan 18;9(1):283. doi: 10.1038/s41467-017-02252-2. Nat Commun. 2018. PMID: 29348454 Free PMC article.

2

Tryp-N: A Thermostable Protease for the Production of N-terminal Argininyl and Lysinyl Peptides.

Wilson JP, Ipsaro JJ, Del Giudice SN, Turna NS, Gauss CM, Dusenbury KH, Marquart K, Rivera KD, Pappin DJ. Wilson JP, et al. Among authors: gauss cm. J Proteome Res. 2020 Apr 3;19(4):1459-1469. doi: 10.1021/acs.jproteome.9b00713. Epub 2020 Mar 20. J Proteome Res. 2020. PMID: 32141294 Free PMC article.

3

Targeting the disordered C terminus of PTP1B with an allosteric inhibitor.

Krishnan N, Koveal D, Miller DH, Xue B, Akshinthala SD, Kragelj J, Jensen MR, Gauss CM, Page R, Blackledge M, Muthuswamy SK, Peti W, Tonks NK. Krishnan N, et al. Among authors: gauss cm. Nat Chem Biol. 2014 Jul;10(7):558-66. doi: 10.1038/nchembio.1528. Epub 2014 May 20. Nat Chem Biol. 2014. PMID: 24845231 Free PMC article.

4

Synthesis and Preliminary Evaluation of Duocarmycin Analogues Incorporating the 1,2,11,11a-Tetrahydrocyclopropa[c]naphtho[2,3-e]indol-4-one (CNI) and 1,2,11,11a-Tetrahydrocyclopropa[c]naphtho[1,2-e]indol-4-one (iso-CNI) Alkylation Subunits.

Gauss CM, Hamasaki A, Parrish JP, Macmillan KS, Rayl TJ, Hwang I, Boger DL. Gauss CM, et al. Tetrahedron. 2009 Aug 15;65(33):6591-6599. doi: 10.1016/j.tet.2009.02.065. Tetrahedron. 2009. PMID: 20161204 Free PMC article.

5

Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition.

Lawhorn BG, Boga SB, Wolkenberg SE, Colby DA, Gauss CM, Swingle MR, Amable L, Honkanen RE, Boger DL. Lawhorn BG, et al. Among authors: gauss cm. J Am Chem Soc. 2006 Dec 27;128(51):16720-32. doi: 10.1021/ja066477d. J Am Chem Soc. 2006. PMID: 17177422 Free PMC article.

6

A human single-chain antibody specific for integrin alpha3beta1 capable of cell internalization and delivery of antitumor agents.

Lillo AM, Sun C, Gao C, Ditzel H, Parrish J, Gauss CM, Moss J, Felding-Habermann B, Wirsching P, Boger DL, Janda KD. Lillo AM, et al. Among authors: gauss cm. Chem Biol. 2004 Jul;11(7):897-906. doi: 10.1016/j.chembiol.2004.04.018. Chem Biol. 2004. PMID: 15271348

7

Fundamental role of the fostriecin unsaturated lactone and implications for selective protein phosphatase inhibition.

Buck SB, Hardouin C, Ichikawa S, Soenen DR, Gauss CM, Hwang I, Swingle MR, Bonness KM, Honkanen RE, Boger DL. Buck SB, et al. Among authors: gauss cm. J Am Chem Soc. 2003 Dec 24;125(51):15694-5. doi: 10.1021/ja038672n. J Am Chem Soc. 2003. PMID: 14677930

8

Fostriecin: chemistry and biology.

Lewy DS, Gauss CM, Soenen DR, Boger DL. Lewy DS, et al. Among authors: gauss cm. Curr Med Chem. 2002 Nov;9(22):2005-32. doi: 10.2174/0929867023368809. Curr Med Chem. 2002. PMID: 12369868 Review.

9

The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity.

Aggen JB, Humphrey JM, Gauss CM, Huang HB, Nairn AC, Chamberlin AR. Aggen JB, et al. Among authors: gauss cm. Bioorg Med Chem. 1999 Mar;7(3):543-64. doi: 10.1016/s0968-0896(98)00254-5. Bioorg Med Chem. 1999. PMID: 10220039

10

A molecular modeling analysis of the binding interactions between the okadaic acid class of natural product inhibitors and the Ser-Thr phosphatases, PP1 and PP2A.

Gauss CM, Sheppeck JE 2nd, Nairn AC, Chamberlin R. Gauss CM, et al. Bioorg Med Chem. 1997 Sep;5(9):1751-73. doi: 10.1016/s0968-0896(97)00145-4. Bioorg Med Chem. 1997. PMID: 9354231 Review.

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