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Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.
Reilly SN, Liu X, Carnicer R, Recalde A, Muszkiewicz A, Jayaram R, Carena MC, Wijesurendra R, Stefanini M, Surdo NC, Lomas O, Ratnatunga C, Sayeed R, Krasopoulos G, Rajakumar T, Bueno-Orovio A, Verheule S, Fulga TA, Rodriguez B, Schotten U, Casadei B. Reilly SN, et al. Among authors: casadei b. Sci Transl Med. 2016 May 25;8(340):340ra74. doi: 10.1126/scitranslmed.aac4296. Sci Transl Med. 2016. PMID: 27225184 Free PMC article.
Dilated cardiomyopathy mutations in thin-filament regulatory proteins reduce contractility, suppress systolic Ca2+, and activate NFAT and Akt signaling.
Robinson P, Sparrow AJ, Patel S, Malinowska M, Reilly SN, Zhang YH, Casadei B, Watkins H, Redwood C. Robinson P, et al. Among authors: casadei b. Am J Physiol Heart Circ Physiol. 2020 Aug 1;319(2):H306-H319. doi: 10.1152/ajpheart.00272.2020. Epub 2020 Jul 3. Am J Physiol Heart Circ Physiol. 2020. PMID: 32618513 Free PMC article.
352 results