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Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells.
Huang SH, Ren Y, Thomas AS, Chan D, Mueller S, Ward AR, Patel S, Bollard CM, Cruz CR, Karandish S, Truong R, Macedo AB, Bosque A, Kovacs C, Benko E, Piechocka-Trocha A, Wong H, Jeng E, Nixon DF, Ho YC, Siliciano RF, Walker BD, Jones RB. Huang SH, et al. Among authors: patel s. J Clin Invest. 2018 Feb 1;128(2):876-889. doi: 10.1172/JCI97555. Epub 2018 Jan 22. J Clin Invest. 2018. PMID: 29355843 Free PMC article.
Functionally Active HIV-Specific T Cells that Target Gag and Nef Can Be Expanded from Virus-Naïve Donors and Target a Range of Viral Epitopes: Implications for a Cure Strategy after Allogeneic Hematopoietic Stem Cell Transplantation.
Patel S, Lam S, Cruz CR, Wright K, Cochran C, Ambinder RF, Bollard CM. Patel S, et al. Biol Blood Marrow Transplant. 2016 Mar;22(3):536-41. doi: 10.1016/j.bbmt.2015.12.007. Epub 2015 Dec 22. Biol Blood Marrow Transplant. 2016. PMID: 26721209 Free PMC article.
A New Method for Reactivating and Expanding T Cells Specific for Rhizopus oryzae.
Castillo P, Wright KE, Kontoyiannis DP, Walsh T, Patel S, Chorvinsky E, Bose S, Hazrat Y, Omer B, Albert N, Leen AM, Rooney CM, Bollard CM, Cruz CRY. Castillo P, et al. Among authors: patel s. Mol Ther Methods Clin Dev. 2018 Mar 14;9:305-312. doi: 10.1016/j.omtm.2018.03.003. eCollection 2018 Jun 15. Mol Ther Methods Clin Dev. 2018. PMID: 30038934 Free PMC article.
HIV-Specific, Ex Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy in ART-Suppressed HIV-Infected Individuals.
Sung JA, Patel S, Clohosey ML, Roesch L, Tripic T, Kuruc JD, Archin N, Hanley PJ, Cruz CR, Goonetilleke N, Eron JJ, Rooney CM, Gay CL, Bollard CM, Margolis DM. Sung JA, et al. Among authors: patel s. Mol Ther. 2018 Oct 3;26(10):2496-2506. doi: 10.1016/j.ymthe.2018.08.015. Epub 2018 Sep 21. Mol Ther. 2018. PMID: 30249388 Free PMC article. Clinical Trial.
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