Cragg MS - Search Results

1

Proteomics Profiling of CLL Versus Healthy B-cells Identifies Putative Therapeutic Targets and a Subtype-independent Signature of Spliceosome Dysregulation.

Johnston HE, Carter MJ, Larrayoz M, Clarke J, Garbis SD, Oscier D, Strefford JC, Steele AJ, Walewska R, Cragg MS. Johnston HE, et al. Among authors: cragg ms. Mol Cell Proteomics. 2018 Apr;17(4):776-791. doi: 10.1074/mcp.RA117.000539. Epub 2018 Jan 24. Mol Cell Proteomics. 2018. PMID: 29367434 Free PMC article.

2

The alternative transcript of CD79b is overexpressed in B-CLL and inhibits signaling for apoptosis.

Cragg MS, Chan HT, Fox MD, Tutt A, Smith A, Oscier DG, Hamblin TJ, Glennie MJ. Cragg MS, et al. Blood. 2002 Nov 1;100(9):3068-76. doi: 10.1182/blood.V100.9.3068. Blood. 2002. PMID: 12384401 Free article.

3

Fc gamma receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy.

Lim SH, Vaughan AT, Ashton-Key M, Williams EL, Dixon SV, Chan HT, Beers SA, French RR, Cox KL, Davies AJ, Potter KN, Mockridge CI, Oscier DG, Johnson PW, Cragg MS, Glennie MJ. Lim SH, et al. Among authors: cragg ms. Blood. 2011 Sep 1;118(9):2530-40. doi: 10.1182/blood-2011-01-330357. Epub 2011 Jul 18. Blood. 2011. PMID: 21768293 Free article.

4

Transforming growth factor-β directly induces p53-up-regulated modulator of apoptosis (PUMA) during the rapid induction of apoptosis in myc-driven B-cell lymphomas.

Spender LC, Carter MJ, O'Brien DI, Clark LJ, Yu J, Michalak EM, Happo L, Cragg MS, Inman GJ. Spender LC, et al. Among authors: cragg ms. J Biol Chem. 2013 Feb 15;288(7):5198-209. doi: 10.1074/jbc.M112.410274. Epub 2012 Dec 14. J Biol Chem. 2013. PMID: 23243310 Free PMC article.

5

Upregulation of FcγRIIb on monocytes is necessary to promote the superagonist activity of TGN1412.

Hussain K, Hargreaves CE, Roghanian A, Oldham RJ, Chan HT, Mockridge CI, Chowdhury F, Frendéus B, Harper KS, Strefford JC, Cragg MS, Glennie MJ, Williams AP, French RR. Hussain K, et al. Among authors: cragg ms. Blood. 2015 Jan 1;125(1):102-10. doi: 10.1182/blood-2014-08-593061. Epub 2014 Nov 13. Blood. 2015. PMID: 25395427 Free article.

6

Role of the pro-survival molecule Bfl-1 in melanoma.

Hind CK, Carter MJ, Harris CL, Chan HT, James S, Cragg MS. Hind CK, et al. Among authors: cragg ms. Int J Biochem Cell Biol. 2015 Feb;59:94-102. doi: 10.1016/j.biocel.2014.11.015. Epub 2014 Dec 6. Int J Biochem Cell Biol. 2015. PMID: 25486183

7

Antigenic modulation limits the effector cell mechanisms employed by type I anti-CD20 monoclonal antibodies.

Tipton TR, Roghanian A, Oldham RJ, Carter MJ, Cox KL, Mockridge CI, French RR, Dahal LN, Duriez PJ, Hargreaves PG, Cragg MS, Beers SA. Tipton TR, et al. Among authors: cragg ms. Blood. 2015 Mar 19;125(12):1901-9. doi: 10.1182/blood-2014-07-588376. Epub 2015 Jan 28. Blood. 2015. PMID: 25631769 Free article.

8

The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model.

Blunt MD, Carter MJ, Larrayoz M, Smith LD, Aguilar-Hernandez M, Cox KL, Tipton T, Reynolds M, Murphy S, Lemm E, Dias S, Duncombe A, Strefford JC, Johnson PW, Forconi F, Stevenson FK, Packham G, Cragg MS, Steele AJ. Blunt MD, et al. Among authors: cragg ms. Blood. 2015 Jun 25;125(26):4032-41. doi: 10.1182/blood-2014-11-610329. Epub 2015 May 8. Blood. 2015. PMID: 25957390 Free article.

9

BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only proteins in a murine model of B-cell lymphoma.

Carter MJ, Cox KL, Blakemore SJ, Bogdanov YD, Happo L, Scott CL, Strasser A, Packham GK, Cragg MS. Carter MJ, et al. Among authors: cragg ms. Cell Death Differ. 2016 Feb;23(2):303-12. doi: 10.1038/cdd.2015.97. Epub 2015 Jul 17. Cell Death Differ. 2016. PMID: 26184912 Free PMC article.

10

The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukaemia cells through downregulation of Mcl-1.

Larrayoz M, Blakemore SJ, Dobson RC, Blunt MD, Rose-Zerilli MJ, Walewska R, Duncombe A, Oscier D, Koide K, Forconi F, Packham G, Yoshida M, Cragg MS, Strefford JC, Steele AJ. Larrayoz M, et al. Among authors: cragg ms. Leukemia. 2016 Feb;30(2):351-60. doi: 10.1038/leu.2015.286. Epub 2015 Oct 21. Leukemia. 2016. PMID: 26488112

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