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Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology.
Praet J, Manyakov NV, Muchene L, Mai Z, Terzopoulos V, de Backer S, Torremans A, Guns PJ, Van De Casteele T, Bottelbergs A, Van Broeck B, Sijbers J, Smeets D, Shkedy Z, Bijnens L, Pemberton DJ, Schmidt ME, Van der Linden A, Verhoye M. Praet J, et al. Among authors: bottelbergs a. Alzheimers Res Ther. 2018 Jan 9;10(1):1. doi: 10.1186/s13195-017-0329-8. Alzheimers Res Ther. 2018. PMID: 29370870 Free PMC article.
Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice.
Peeraer E, Bottelbergs A, Van Kolen K, Stancu IC, Vasconcelos B, Mahieu M, Duytschaever H, Ver Donck L, Torremans A, Sluydts E, Van Acker N, Kemp JA, Mercken M, Brunden KR, Trojanowski JQ, Dewachter I, Lee VM, Moechars D. Peeraer E, et al. Among authors: bottelbergs a. Neurobiol Dis. 2015 Jan;73:83-95. doi: 10.1016/j.nbd.2014.08.032. Epub 2014 Sep 16. Neurobiol Dis. 2015. PMID: 25220759 Free PMC article.
Evaluation of Small-Animal PET Outcome Measures to Detect Disease Modification Induced by BACE Inhibition in a Transgenic Mouse Model of Alzheimer Disease.
Deleye S, Waldron AM, Verhaeghe J, Bottelbergs A, Wyffels L, Van Broeck B, Langlois X, Schmidt M, Stroobants S, Staelens S. Deleye S, et al. Among authors: bottelbergs a. J Nucl Med. 2017 Dec;58(12):1977-1983. doi: 10.2967/jnumed.116.187625. Epub 2017 Jun 13. J Nucl Med. 2017. PMID: 28611242 Free article.
S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-β Plaques and Tau in Brain Biopsies.
Leinonen V, Rauramaa T, Johansson J, Bottelbergs A, Tesseur I, van der Ark P, Pemberton D, Koivisto AM, Jääskeläinen JE, Hiltunen M, Herukka SK, Blennow K, Zetterberg H, Jokinen P, Rokka J, Helin S, Haaparanta-Solin M, Solin O, Okamura N, Kolb HC, Rinne JO. Leinonen V, et al. Among authors: bottelbergs a. J Alzheimers Dis. 2018;64(1):171-179. doi: 10.3233/JAD-180071. J Alzheimers Dis. 2018. PMID: 29865068
Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo.
Vandermeeren M, Borgers M, Van Kolen K, Theunis C, Vasconcelos B, Bottelbergs A, Wintmolders C, Daneels G, Willems R, Dockx K, Delbroek L, Marreiro A, Ver Donck L, Sousa C, Nanjunda R, Lacy E, Van De Casteele T, Van Dam D, De Deyn PP, Kemp JA, Malia TJ, Mercken MH. Vandermeeren M, et al. Among authors: bottelbergs a. J Alzheimers Dis. 2018;65(1):265-281. doi: 10.3233/JAD-180404. J Alzheimers Dis. 2018. PMID: 30040731
Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody.
Van Kolen K, Malia TJ, Theunis C, Nanjunda R, Teplyakov A, Ernst R, Wu SJ, Luo J, Borgers M, Vandermeeren M, Bottelbergs A, Wintmolders C, Lacy E, Maurin H, Larsen P, Willems R, Van De Casteele T, Triana-Baltzer G, Slemmon R, Galpern W, Trojanowski JQ, Sun H, Mercken MH. Van Kolen K, et al. Among authors: bottelbergs a. J Alzheimers Dis. 2020;77(4):1397-1416. doi: 10.3233/JAD-200544. J Alzheimers Dis. 2020. PMID: 32894244
34 results