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Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology.
Praet J, Manyakov NV, Muchene L, Mai Z, Terzopoulos V, de Backer S, Torremans A, Guns PJ, Van De Casteele T, Bottelbergs A, Van Broeck B, Sijbers J, Smeets D, Shkedy Z, Bijnens L, Pemberton DJ, Schmidt ME, Van der Linden A, Verhoye M. Praet J, et al. Among authors: pemberton dj. Alzheimers Res Ther. 2018 Jan 9;10(1):1. doi: 10.1186/s13195-017-0329-8. Alzheimers Res Ther. 2018. PMID: 29370870 Free PMC article.
Synthesis and Evaluation of a Zr-89-Labeled Monoclonal Antibody for Immuno-PET Imaging of Amyloid-β Deposition in the Brain.
Fissers J, Waldron AM, De Vijlder T, Van Broeck B, Pemberton DJ, Mercken M, Van Der Veken P, Joossens J, Augustyns K, Dedeurwaerdere S, Stroobants S, Staelens S, Wyffels L. Fissers J, et al. Among authors: pemberton dj. Mol Imaging Biol. 2016 Aug;18(4):598-605. doi: 10.1007/s11307-016-0935-z. Mol Imaging Biol. 2016. PMID: 26846128
S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-β Plaques and Tau in Brain Biopsies.
Leinonen V, Rauramaa T, Johansson J, Bottelbergs A, Tesseur I, van der Ark P, Pemberton D, Koivisto AM, Jääskeläinen JE, Hiltunen M, Herukka SK, Blennow K, Zetterberg H, Jokinen P, Rokka J, Helin S, Haaparanta-Solin M, Solin O, Okamura N, Kolb HC, Rinne JO. Leinonen V, et al. J Alzheimers Dis. 2018;64(1):171-179. doi: 10.3233/JAD-180071. J Alzheimers Dis. 2018. PMID: 29865068
In Vivo Amyloid-β Imaging in the APPPS1-21 Transgenic Mouse Model with a (89)Zr-Labeled Monoclonal Antibody.
Waldron AM, Fissers J, Van Eetveldt A, Van Broeck B, Mercken M, Pemberton DJ, Van Der Veken P, Augustyns K, Joossens J, Stroobants S, Dedeurwaerdere S, Wyffels L, Staelens S. Waldron AM, et al. Among authors: pemberton dj. Front Aging Neurosci. 2016 Mar 31;8:67. doi: 10.3389/fnagi.2016.00067. eCollection 2016. Front Aging Neurosci. 2016. PMID: 27064204 Free PMC article.
Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus.
Lukkarinen H, Tesseur I, Pemberton D, Van Der Ark P, Timmers M, Slemmon R, Janssens L, Streffer J, Van Nueten L, Bottelbergs A, Rauramaa T, Koivisto AM, Herukka SK, Korhonen VE, Junkkari A, Hiltunen M, Engelborghs S, Blennow K, Zetterberg H, Kolb HC, Leinonen V. Lukkarinen H, et al. J Alzheimers Dis. 2021;80(4):1629-1642. doi: 10.3233/JAD-201361. J Alzheimers Dis. 2021. PMID: 33720890 Free PMC article.
Fatty Acid Amide Hydrolase Inhibition by JNJ-42165279: A Multiple-Ascending Dose and a Positron Emission Tomography Study in Healthy Volunteers.
Postnov A, Schmidt ME, Pemberton DJ, de Hoon J, van Hecken A, van den Boer M, Zannikos P, van der Ark P, Palmer JA, Rassnick S, Celen S, Bormans G, van Laere K. Postnov A, et al. Among authors: pemberton dj. Clin Transl Sci. 2018 Jul;11(4):397-404. doi: 10.1111/cts.12548. Epub 2018 Mar 25. Clin Transl Sci. 2018. PMID: 29575526 Free PMC article. Clinical Trial.
The effects of inhibition of fatty acid amide hydrolase (FAAH) by JNJ-42165279 in social anxiety disorder: a double-blind, randomized, placebo-controlled proof-of-concept study.
Schmidt ME, Liebowitz MR, Stein MB, Grunfeld J, Van Hove I, Simmons WK, Van Der Ark P, Palmer JA, Saad ZS, Pemberton DJ, Van Nueten L, Drevets WC. Schmidt ME, et al. Among authors: pemberton dj. Neuropsychopharmacology. 2021 Apr;46(5):1004-1010. doi: 10.1038/s41386-020-00888-1. Epub 2020 Oct 18. Neuropsychopharmacology. 2021. PMID: 33070154 Free PMC article. Clinical Trial.
In vitro and in vivo characterization of the non-peptide NK3 receptor antagonist SB-223412 (talnetant): potential therapeutic utility in the treatment of schizophrenia.
Dawson LA, Cato KJ, Scott C, Watson JM, Wood MD, Foxton R, de la Flor R, Jones GA, Kew JN, Cluderay JE, Southam E, Murkitt GS, Gartlon J, Pemberton DJ, Jones DN, Davies CH, Hagan J. Dawson LA, et al. Among authors: pemberton dj. Neuropsychopharmacology. 2008 Jun;33(7):1642-52. doi: 10.1038/sj.npp.1301549. Epub 2007 Aug 29. Neuropsychopharmacology. 2008. PMID: 17728699
37 results