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Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology.
Praet J, Manyakov NV, Muchene L, Mai Z, Terzopoulos V, de Backer S, Torremans A, Guns PJ, Van De Casteele T, Bottelbergs A, Van Broeck B, Sijbers J, Smeets D, Shkedy Z, Bijnens L, Pemberton DJ, Schmidt ME, Van der Linden A, Verhoye M. Praet J, et al. Alzheimers Res Ther. 2018 Jan 9;10(1):1. doi: 10.1186/s13195-017-0329-8. Alzheimers Res Ther. 2018. PMID: 29370870 Free PMC article.
Diffusion kurtosis imaging probes cortical alterations and white matter pathology following cuprizone induced demyelination and spontaneous remyelination.
Guglielmetti C, Veraart J, Roelant E, Mai Z, Daans J, Van Audekerke J, Naeyaert M, Vanhoutte G, Delgado Y Palacios R, Praet J, Fieremans E, Ponsaerts P, Sijbers J, Van der Linden A, Verhoye M. Guglielmetti C, et al. Among authors: praet j. Neuroimage. 2016 Jan 15;125:363-377. doi: 10.1016/j.neuroimage.2015.10.052. Epub 2015 Oct 23. Neuroimage. 2016. PMID: 26525654 Free PMC article.
Early pathologic amyloid induces hypersynchrony of BOLD resting-state networks in transgenic mice and provides an early therapeutic window before amyloid plaque deposition.
Shah D, Praet J, Latif Hernandez A, Höfling C, Anckaerts C, Bard F, Morawski M, Detrez JR, Prinsen E, Villa A, De Vos WH, Maggi A, D'Hooge R, Balschun D, Rossner S, Verhoye M, Van der Linden A. Shah D, et al. Among authors: praet j. Alzheimers Dement. 2016 Sep;12(9):964-976. doi: 10.1016/j.jalz.2016.03.010. Epub 2016 Apr 21. Alzheimers Dement. 2016. PMID: 27107518
Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model.
Le Blon D, Guglielmetti C, Hoornaert C, Quarta A, Daans J, Dooley D, Lemmens E, Praet J, De Vocht N, Reekmans K, Santermans E, Hens N, Goossens H, Verhoye M, Van der Linden A, Berneman Z, Hendrix S, Ponsaerts P. Le Blon D, et al. Among authors: praet j. J Neuroinflammation. 2016 Nov 9;13(1):288. doi: 10.1186/s12974-016-0756-7. J Neuroinflammation. 2016. PMID: 27829467 Free PMC article.
Multimodal imaging of subventricular zone neural stem/progenitor cells in the cuprizone mouse model reveals increased neurogenic potential for the olfactory bulb pathway, but no contribution to remyelination of the corpus callosum.
Guglielmetti C, Praet J, Rangarajan JR, Vreys R, De Vocht N, Maes F, Verhoye M, Ponsaerts P, Van der Linden A. Guglielmetti C, et al. Among authors: praet j. Neuroimage. 2014 Feb 1;86:99-110. doi: 10.1016/j.neuroimage.2013.07.080. Epub 2013 Aug 7. Neuroimage. 2014. PMID: 23933305 Free article.
Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages.
Guglielmetti C, Le Blon D, Santermans E, Salas-Perdomo A, Daans J, De Vocht N, Shah D, Hoornaert C, Praet J, Peerlings J, Kara F, Bigot C, Mai Z, Goossens H, Hens N, Hendrix S, Verhoye M, Planas AM, Berneman Z, van der Linden A, Ponsaerts P. Guglielmetti C, et al. Among authors: praet j. Glia. 2016 Dec;64(12):2181-2200. doi: 10.1002/glia.23053. Epub 2016 Sep 29. Glia. 2016. PMID: 27685637
178 results