Ahring PK - Search Results

1

The flavonoid, 2'-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia.

Clarkson AN, Boothman-Burrell L, Dósa Z, Nagaraja RY, Jin L, Parker K, van Nieuwenhuijzen PS, Neumann S, Gowing EK, Gavande N, Ahring PK, Holm MM, Hanrahan JR, Nicolazzo JA, Jensen K, Chebib M. Clarkson AN, et al. Among authors: ahring pk. J Cereb Blood Flow Metab. 2019 Jul;39(7):1266-1282. doi: 10.1177/0271678X18755628. Epub 2018 Jan 29. J Cereb Blood Flow Metab. 2019. PMID: 29376464 Free PMC article.

2

High and low GABA sensitivity α4β2δ GABAA receptors are expressed in Xenopus laevis oocytes with divergent stoichiometries.

Hartiadi LY, Ahring PK, Chebib M, Absalom NL. Hartiadi LY, et al. Among authors: ahring pk. Biochem Pharmacol. 2016 Mar 1;103:98-108. doi: 10.1016/j.bcp.2015.12.021. Epub 2016 Jan 13. Biochem Pharmacol. 2016. PMID: 26774457

3

A pharmacological assessment of agonists and modulators at α4β2γ2 and α4β2δ GABAA receptors: The challenge in comparing apples with oranges.

Ahring PK, Bang LH, Jensen ML, Strøbæk D, Hartiadi LY, Chebib M, Absalom N. Ahring PK, et al. Pharmacol Res. 2016 Sep;111:563-576. doi: 10.1016/j.phrs.2016.05.014. Epub 2016 May 10. Pharmacol Res. 2016. PMID: 27178730

4

A pharmacological characterization of GABA, THIP and DS2 at binary α4β3 and β3δ receptors: GABA activates β3δ receptors via the β3(+)δ(-) interface.

Lee HJ, Absalom NL, Hanrahan JR, van Nieuwenhuijzen P, Ahring PK, Chebib M. Lee HJ, et al. Among authors: ahring pk. Brain Res. 2016 Aug 1;1644:222-30. doi: 10.1016/j.brainres.2016.05.019. Epub 2016 May 12. Brain Res. 2016. PMID: 27181518

5

Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABAA receptors: evidence of a novel benzodiazepine site in the α1-α1 interface.

Che Has AT, Absalom N, van Nieuwenhuijzen PS, Clarkson AN, Ahring PK, Chebib M. Che Has AT, et al. Among authors: ahring pk. Sci Rep. 2016 Jun 27;6:28674. doi: 10.1038/srep28674. Sci Rep. 2016. PMID: 27346730 Free PMC article.

6

Ligand Binding at the 4-4 Agonist-Binding Site of the 42 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State.

Indurthi DC, Lewis TM, Ahring PK, Balle T, Chebib M, Absalom NL. Indurthi DC, et al. Among authors: ahring pk. PLoS One. 2016 Aug 23;11(8):e0161154. doi: 10.1371/journal.pone.0161154. eCollection 2016. PLoS One. 2016. PMID: 27552221 Free PMC article.

7

Galantamine is not a positive allosteric modulator of human α4β2 or α7 nicotinic acetylcholine receptors.

Kowal NM, Ahring PK, Liao VWY, Indurti DC, Harvey BS, O'Connor SM, Chebib M, Olafsdottir ES, Balle T. Kowal NM, et al. Among authors: ahring pk. Br J Pharmacol. 2018 Jul;175(14):2911-2925. doi: 10.1111/bph.14329. Epub 2018 Jun 7. Br J Pharmacol. 2018. PMID: 29669164 Free PMC article.

8

Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry.

Indurthi DC, Qudah T, Liao VW, Ahring PK, Lewis TM, Balle T, Chebib M, Absalom NL. Indurthi DC, et al. Among authors: ahring pk. Pharmacol Res. 2019 Jan;139:215-227. doi: 10.1016/j.phrs.2018.11.031. Epub 2018 Nov 22. Pharmacol Res. 2019. PMID: 30472464

9

Novel Approach for the Search for Chemical Scaffolds with Dual Activity with Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor-A Perspective for the Treatment of Neurodegenerative Disorders.

Kowal NM, Indurthi DC, Ahring PK, Chebib M, Olafsdottir ES, Balle T. Kowal NM, et al. Among authors: ahring pk. Molecules. 2019 Jan 27;24(3):446. doi: 10.3390/molecules24030446. Molecules. 2019. PMID: 30691196 Free PMC article.

10

Functional genomics of epilepsy-associated mutations in the GABA_A receptor subunits reveal that one mutation impairs function and two are catastrophic.

Absalom NL, Ahring PK, Liao VW, Balle T, Jiang T, Anderson LL, Arnold JC, McGregor IS, Bowen MT, Chebib M. Absalom NL, et al. Among authors: ahring pk. J Biol Chem. 2019 Apr 12;294(15):6157-6171. doi: 10.1074/jbc.RA118.005697. Epub 2019 Feb 6. J Biol Chem. 2019. PMID: 30728247 Free PMC article.

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