O'Neill E - Search Results

1

RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.

Papaspyropoulos A, Bradley L, Thapa A, Leung CY, Toskas K, Koennig D, Pefani DE, Raso C, Grou C, Hamilton G, Vlahov N, Grawenda A, Haider S, Chauhan J, Buti L, Kanapin A, Lu X, Buffa F, Dianov G, von Kriegsheim A, Matallanas D, Samsonova A, Zernicka-Goetz M, O'Neill E. Papaspyropoulos A, et al. Nat Commun. 2018 Jan 30;9(1):424. doi: 10.1038/s41467-017-02786-5. Nat Commun. 2018. PMID: 29382819 Free PMC article.

2

Mammalian sterile 20-like kinases in tumor suppression: an emerging pathway.

O'Neill EE, Matallanas D, Kolch W. O'Neill EE, et al. Cancer Res. 2005 Jul 1;65(13):5485-7. doi: 10.1158/0008-5472.CAN-05-1453. Cancer Res. 2005. PMID: 15994916 Review.

3

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein.

Matallanas D, Romano D, Yee K, Meissl K, Kucerova L, Piazzolla D, Baccarini M, Vass JK, Kolch W, O'neill E. Matallanas D, et al. Mol Cell. 2007 Sep 21;27(6):962-75. doi: 10.1016/j.molcel.2007.08.008. Mol Cell. 2007. PMID: 17889669 Free PMC article.

4

A Hippo in the ointment: MST signalling beyond the fly.

Matallanas D, Romano D, Hamilton G, Kolch W, O'Neill E. Matallanas D, et al. Cell Cycle. 2008 Apr 1;7(7):879-84. doi: 10.4161/cc.7.7.5630. Epub 2008 Jan 22. Cell Cycle. 2008. PMID: 18414046 Review.

5

RAN GTPase is a RASSF1A effector involved in controlling microtubule organization.

Dallol A, Hesson LB, Matallanas D, Cooper WN, O'Neill E, Maher ER, Kolch W, Latif F. Dallol A, et al. Curr Biol. 2009 Jul 28;19(14):1227-32. doi: 10.1016/j.cub.2009.05.064. Epub 2009 Jun 25. Curr Biol. 2009. PMID: 19559616 Free article.

6

ATM regulates a RASSF1A-dependent DNA damage response.

Hamilton G, Yee KS, Scrace S, O'Neill E. Hamilton G, et al. Curr Biol. 2009 Dec 15;19(23):2020-5. doi: 10.1016/j.cub.2009.10.040. Epub 2009 Dec 3. Curr Biol. 2009. PMID: 19962312 Free PMC article.

7

Analysis of conditions affecting auto-phosphorylation of human kinases during expression in bacteria.

Shrestha A, Hamilton G, O'Neill E, Knapp S, Elkins JM. Shrestha A, et al. Protein Expr Purif. 2012 Jan;81(1):136-143. doi: 10.1016/j.pep.2011.09.012. Epub 2011 Oct 1. Protein Expr Purif. 2012. PMID: 21985771 Free PMC article.

8

Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras.

Matallanas D, Romano D, Al-Mulla F, O'Neill E, Al-Ali W, Crespo P, Doyle B, Nixon C, Sansom O, Drosten M, Barbacid M, Kolch W. Matallanas D, et al. Mol Cell. 2011 Dec 23;44(6):893-906. doi: 10.1016/j.molcel.2011.10.016. Mol Cell. 2011. PMID: 22195963 Free article.

9

A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma.

Yee KS, Grochola L, Hamilton G, Grawenda A, Bond EE, Taubert H, Wurl P, Bond GL, O'Neill E. Yee KS, et al. Cancer Res. 2012 May 1;72(9):2206-17. doi: 10.1158/0008-5472.CAN-11-2906. Epub 2012 Mar 2. Cancer Res. 2012. PMID: 22389451 Free PMC article.

10

Loss of RASSF1A synergizes with deregulated RUNX2 signaling in tumorigenesis.

van der Weyden L, Papaspyropoulos A, Poulogiannis G, Rust AG, Rashid M, Adams DJ, Arends MJ, O'Neill E. van der Weyden L, et al. Cancer Res. 2012 Aug 1;72(15):3817-3827. doi: 10.1158/0008-5472.CAN-11-3343. Epub 2012 Jun 18. Cancer Res. 2012. PMID: 22710434 Free PMC article.

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