Sun Y - Search Results

1

Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2-MRN-ATM axes.

Zhao Y, Tan M, Liu X, Xiong X, Sun Y. Zhao Y, et al. Among authors: sun y. Cell Death Dis. 2018 Feb 2;9(2):145. doi: 10.1038/s41419-017-0192-3. Cell Death Dis. 2018. PMID: 29396424 Free PMC article.

2

Histone deacetylase 5 is not a p53 target gene, but its overexpression inhibits tumor cell growth and induces apoptosis.

Huang Y, Tan M, Gosink M, Wang KK, Sun Y. Huang Y, et al. Among authors: sun y. Cancer Res. 2002 May 15;62(10):2913-22. Cancer Res. 2002. PMID: 12019172

3

SAK, a new polo-like kinase, is transcriptionally repressed by p53 and induces apoptosis upon RNAi silencing.

Li J, Tan M, Li L, Pamarthy D, Lawrence TS, Sun Y. Li J, et al. Among authors: sun y. Neoplasia. 2005 Apr;7(4):312-23. doi: 10.1593/neo.04325. Neoplasia. 2005. PMID: 15967108 Free PMC article.

4

A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells.

Bockbrader KM, Tan M, Sun Y. Bockbrader KM, et al. Among authors: sun y. Oncogene. 2005 Nov 10;24(49):7381-8. doi: 10.1038/sj.onc.1208888. Oncogene. 2005. PMID: 16044155

5

p53 and its downstream proteins as molecular targets of cancer.

Sun Y. Sun Y. Mol Carcinog. 2006 Jun;45(6):409-15. doi: 10.1002/mc.20231. Mol Carcinog. 2006. PMID: 16652354 Free article. Review.

6

CK2 phosphorylation of SAG at Thr10 regulates SAG stability, but not its E3 ligase activity.

He H, Tan M, Pamarthy D, Wang G, Ahmed K, Sun Y. He H, et al. Among authors: sun y. Mol Cell Biochem. 2007 Jan;295(1-2):179-88. doi: 10.1007/s11010-006-9287-3. Epub 2006 Jul 28. Mol Cell Biochem. 2007. PMID: 16874460

7

SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection.

Tan M, Gallegos JR, Gu Q, Huang Y, Li J, Jin Y, Lu H, Sun Y. Tan M, et al. Among authors: sun y. Neoplasia. 2006 Dec;8(12):1042-54. doi: 10.1593/neo.06568. Neoplasia. 2006. PMID: 17217622 Free PMC article.

8

p27 degradation by an ellipticinium series of compound via ubiquitin-proteasome pathway.

Pamarthy D, Tan M, Wu M, Chen J, Yang D, Wang S, Zhang H, Sun Y. Pamarthy D, et al. Among authors: sun y. Cancer Biol Ther. 2007 Mar;6(3):360-6. doi: 10.4161/cbt.6.3.3703. Epub 2007 Mar 12. Cancer Biol Ther. 2007. PMID: 17312389 Free article.

9

SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-O-tetradecanoylphorbol-13-acetate-induced neoplastic transformation.

Gu Q, Tan M, Sun Y. Gu Q, et al. Among authors: sun y. Cancer Res. 2007 Apr 15;67(8):3616-25. doi: 10.1158/0008-5472.CAN-06-4020. Cancer Res. 2007. PMID: 17440073

10

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition.

Shangary S, Qin D, McEachern D, Liu M, Miller RS, Qiu S, Nikolovska-Coleska Z, Ding K, Wang G, Chen J, Bernard D, Zhang J, Lu Y, Gu Q, Shah RB, Pienta KJ, Ling X, Kang S, Guo M, Sun Y, Yang D, Wang S. Shangary S, et al. Among authors: sun y. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3933-8. doi: 10.1073/pnas.0708917105. Epub 2008 Mar 3. Proc Natl Acad Sci U S A. 2008. PMID: 18316739 Free PMC article.

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