Voelkel-Johnson C - Search Results

1

N-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner.

Scheffel MJ, Scurti G, Wyatt MM, Garrett-Mayer E, Paulos CM, Nishimura MI, Voelkel-Johnson C. Scheffel MJ, et al. Cancer Immunol Immunother. 2018 Apr;67(4):691-702. doi: 10.1007/s00262-018-2120-5. Epub 2018 Feb 2. Cancer Immunol Immunother. 2018. PMID: 29396710 Free PMC article.

2

Oxidative stress and lymphocyte persistence: implications in immunotherapy.

Mehrotra S, Mougiakakos D, Johansson CC, Voelkel-Johnson C, Kiessling R. Mehrotra S, et al. Adv Cancer Res. 2009;102:197-227. doi: 10.1016/S0065-230X(09)02006-5. Adv Cancer Res. 2009. PMID: 19595310 Review.

3

Inhibition of superoxide generation upon T-cell receptor engagement rescues Mart-1(27-35)-reactive T cells from activation-induced cell death.

Norell H, Martins da Palma T, Lesher A, Kaur N, Mehrotra M, Naga OS, Spivey N, Olafimihan S, Chakraborty NG, Voelkel-Johnson C, Nishimura MI, Mukherji B, Mehrotra S. Norell H, et al. Cancer Res. 2009 Aug 1;69(15):6282-9. doi: 10.1158/0008-5472.CAN-09-1176. Epub 2009 Jul 28. Cancer Res. 2009. PMID: 19638595 Free PMC article.

4

T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules.

Kaur N, Naga OS, Norell H, Al-Khami AA, Scheffel MJ, Chakraborty NG, Voelkel-Johnson C, Mukherji B, Mehrotra S. Kaur N, et al. Cytokine. 2011 Aug;55(2):307-17. doi: 10.1016/j.cyto.2011.04.014. Epub 2011 May 23. Cytokine. 2011. PMID: 21602054 Free PMC article.

5

Polymer-enhanced delivery increases adenoviral gene expression in an orthotopic model of bladder cancer.

Gosnell H, Kasman LM, Potta T, Vu L, Garrett-Mayer E, Rege K, Voelkel-Johnson C. Gosnell H, et al. J Control Release. 2014 Feb 28;176:35-43. doi: 10.1016/j.jconrel.2013.12.012. Epub 2013 Dec 24. J Control Release. 2014. PMID: 24370892 Free PMC article.

6

Promoting thiol expression increases the durability of antitumor T-cell functions.

Kesarwani P, Al-Khami AA, Scurti G, Thyagarajan K, Kaur N, Husain S, Fang Q, Naga OS, Simms P, Beeson G, Voelkel-Johnson C, Garrett-Mayer E, Beeson CC, Nishimura MI, Mehrotra S. Kesarwani P, et al. Cancer Res. 2014 Nov 1;74(21):6036-6047. doi: 10.1158/0008-5472.CAN-14-1084. Epub 2014 Aug 27. Cancer Res. 2014. PMID: 25164014 Free PMC article.

7

Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner.

Tirodkar TS, Lu P, Bai A, Scheffel MJ, Gencer S, Garrett-Mayer E, Bielawska A, Ogretmen B, Voelkel-Johnson C. Tirodkar TS, et al. J Biol Chem. 2015 May 22;290(21):13157-67. doi: 10.1074/jbc.M114.631325. Epub 2015 Apr 3. J Biol Chem. 2015. PMID: 25839235 Free PMC article.

8

The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo.

Venant H, Rahmaniyan M, Jones EE, Lu P, Lilly MB, Garrett-Mayer E, Drake RR, Kraveka JM, Smith CD, Voelkel-Johnson C. Venant H, et al. Mol Cancer Ther. 2015 Dec;14(12):2744-52. doi: 10.1158/1535-7163.MCT-15-0279. Epub 2015 Oct 22. Mol Cancer Ther. 2015. PMID: 26494858 Free PMC article.

9

Efficacy of Adoptive T-cell Therapy Is Improved by Treatment with the Antioxidant N-Acetyl Cysteine, Which Limits Activation-Induced T-cell Death.

Scheffel MJ, Scurti G, Simms P, Garrett-Mayer E, Mehrotra S, Nishimura MI, Voelkel-Johnson C. Scheffel MJ, et al. Cancer Res. 2016 Oct 15;76(20):6006-6016. doi: 10.1158/0008-5472.CAN-16-0587. Cancer Res. 2016. PMID: 27742673 Free PMC article.

10

Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis.

Scheffel MJ, Helke K, Lu P, Bowers JS, Ogretmen B, Garrett-Mayer E, Paulos CM, Voelkel-Johnson C. Scheffel MJ, et al. Sci Rep. 2017 Nov 14;7(1):15552. doi: 10.1038/s41598-017-15791-x. Sci Rep. 2017. PMID: 29138469 Free PMC article.

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