Kopan R - Search Results

1

Glomerular endothelial cell maturation depends on ADAM10, a key regulator of Notch signaling.

Farber G, Hurtado R, Loh S, Monette S, Mtui J, Kopan R, Quaggin S, Meyer-Schwesinger C, Herzlinger D, Scott RP, Blobel CP. Farber G, et al. Among authors: kopan r. Angiogenesis. 2018 May;21(2):335-347. doi: 10.1007/s10456-018-9599-4. Epub 2018 Feb 3. Angiogenesis. 2018. PMID: 29397483 Free PMC article.

2

Epidermal ADAM17 is dispensable for notch activation.

Groot AJ, Cobzaru C, Weber S, Saftig P, Blobel CP, Kopan R, Vooijs M, Franzke CW. Groot AJ, et al. Among authors: kopan r. J Invest Dermatol. 2013 Sep;133(9):2286-8. doi: 10.1038/jid.2013.162. Epub 2013 Apr 3. J Invest Dermatol. 2013. PMID: 23657465 Free PMC article. No abstract available.

3

Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration.

Swaminathan B, Youn SW, Naiche LA, Du J, Villa SR, Metz JB, Feng H, Zhang C, Kopan R, Sims PA, Kitajewski JK. Swaminathan B, et al. Among authors: kopan r. Sci Rep. 2022 Jan 31;12(1):1655. doi: 10.1038/s41598-022-05666-1. Sci Rep. 2022. PMID: 35102202 Free PMC article.

4

Metalloprotease ADAM10 is required for Notch1 site 2 cleavage.

van Tetering G, van Diest P, Verlaan I, van der Wall E, Kopan R, Vooijs M. van Tetering G, et al. Among authors: kopan r. J Biol Chem. 2009 Nov 6;284(45):31018-27. doi: 10.1074/jbc.M109.006775. Epub 2009 Sep 2. J Biol Chem. 2009. PMID: 19726682 Free PMC article.

5

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate.

Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R. Morimoto M, et al. Among authors: kopan r. J Cell Sci. 2010 Jan 15;123(Pt 2):213-24. doi: 10.1242/jcs.058669. J Cell Sci. 2010. PMID: 20048339 Free PMC article.

6

Notch signaling.

Kopan R. Kopan R. Cold Spring Harb Perspect Biol. 2012 Oct 1;4(10):a011213. doi: 10.1101/cshperspect.a011213. Cold Spring Harb Perspect Biol. 2012. PMID: 23028119 Free PMC article. Review.

7

Alagille, Notch, and robustness: why duplicating systems does not ensure redundancy.

Kopan R, Chen S, Liu Z. Kopan R, et al. Pediatr Nephrol. 2014 Apr;29(4):651-7. doi: 10.1007/s00467-013-2661-y. Epub 2013 Nov 24. Pediatr Nephrol. 2014. PMID: 24271660 Free PMC article. Review.

8

Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development.

Boyle SC, Liu Z, Kopan R. Boyle SC, et al. Among authors: kopan r. Development. 2014 Jan;141(2):346-54. doi: 10.1242/dev.100271. Epub 2013 Dec 18. Development. 2014. PMID: 24353058 Free PMC article.

9

Notch signaling regulates gastric antral LGR5 stem cell function.

Demitrack ES, Gifford GB, Keeley TM, Carulli AJ, VanDussen KL, Thomas D, Giordano TJ, Liu Z, Kopan R, Samuelson LC. Demitrack ES, et al. Among authors: kopan r. EMBO J. 2015 Oct 14;34(20):2522-36. doi: 10.15252/embj.201490583. Epub 2015 Aug 12. EMBO J. 2015. PMID: 26271103 Free PMC article.

10

The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.

Kovall RA, Gebelein B, Sprinzak D, Kopan R. Kovall RA, et al. Among authors: kopan r. Dev Cell. 2017 May 8;41(3):228-241. doi: 10.1016/j.devcel.2017.04.001. Dev Cell. 2017. PMID: 28486129 Free PMC article. Review.

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