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Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.
Dolles D, Hoffmann M, Gunesch S, Marinelli O, Möller J, Santoni G, Chatonnet A, Lohse MJ, Wittmann HJ, Strasser A, Nabissi M, Maurice T, Decker M. Dolles D, et al. Among authors: lohse mj. J Med Chem. 2018 Feb 22;61(4):1646-1663. doi: 10.1021/acs.jmedchem.7b01760. Epub 2018 Feb 5. J Med Chem. 2018. PMID: 29400965
Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB1R) "Cis-On" Agonist.
Rodríguez-Soacha DA, Steinmüller SAM, Işbilir A, Fender J, Deventer MH, Ramírez YA, Tutov A, Sotriffer C, Stove CP, Lorenz K, Lohse MJ, Hislop JN, Decker M. Rodríguez-Soacha DA, et al. Among authors: lohse mj. ACS Chem Neurosci. 2022 Aug 17;13(16):2410-2435. doi: 10.1021/acschemneuro.2c00160. Epub 2022 Jul 26. ACS Chem Neurosci. 2022. PMID: 35881914
Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists.
Işbilir A, Möller J, Arimont M, Bobkov V, Perpiñá-Viciano C, Hoffmann C, Inoue A, Heukers R, de Graaf C, Smit MJ, Annibale P, Lohse MJ. Işbilir A, et al. Among authors: lohse mj. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29144-29154. doi: 10.1073/pnas.2013319117. Epub 2020 Nov 4. Proc Natl Acad Sci U S A. 2020. PMID: 33148803 Free PMC article.
356 results