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Page 1
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.
Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts SABM, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slütter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E. Seijkens TTP, et al. Among authors: fay f. J Am Coll Cardiol. 2018 Feb 6;71(5):527-542. doi: 10.1016/j.jacc.2017.11.055. J Am Coll Cardiol. 2018. PMID: 29406859 Free PMC article.
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates.
Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R. Lameijer M, et al. Among authors: fay f. Nat Biomed Eng. 2018 May;2(5):279-292. doi: 10.1038/s41551-018-0221-2. Epub 2018 Apr 16. Nat Biomed Eng. 2018. PMID: 30936448 Free PMC article.
Immune cell screening of a nanoparticle library improves atherosclerosis therapy.
Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ. Tang J, et al. Among authors: fay f. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6731-E6740. doi: 10.1073/pnas.1609629113. Epub 2016 Oct 17. Proc Natl Acad Sci U S A. 2016. PMID: 27791119 Free PMC article.
Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis.
Beldman TJ, Senders ML, Alaarg A, Pérez-Medina C, Tang J, Zhao Y, Fay F, Deichmöller J, Born B, Desclos E, van der Wel NN, Hoebe RA, Kohen F, Kartvelishvily E, Neeman M, Reiner T, Calcagno C, Fayad ZA, de Winther MPJ, Lutgens E, Mulder WJM, Kluza E. Beldman TJ, et al. Among authors: fay f. ACS Nano. 2017 Jun 27;11(6):5785-5799. doi: 10.1021/acsnano.7b01385. Epub 2017 May 15. ACS Nano. 2017. PMID: 28463501 Free PMC article.
Prosaposin mediates inflammation in atherosclerosis.
van Leent MMT, Beldman TJ, Toner YC, Lameijer MA, Rother N, Bekkering S, Teunissen AJP, Zhou X, van der Meel R, Malkus J, Nauta SA, Klein ED, Fay F, Sanchez-Gaytan BL, Pérez-Medina C, Kluza E, Ye YX, Wojtkiewicz G, Fisher EA, Swirski FK, Nahrendorf M, Zhang B, Li Y, Zhang B, Joosten LAB, Pasterkamp G, Boltjes A, Fayad ZA, Lutgens E, Netea MG, Riksen NP, Mulder WJM, Duivenvoorden R. van Leent MMT, et al. Among authors: fay f. Sci Transl Med. 2021 Mar 10;13(584):eabe1433. doi: 10.1126/scitranslmed.abe1433. Sci Transl Med. 2021. PMID: 33692130 Free PMC article.
Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species.
Binderup T, Duivenvoorden R, Fay F, van Leent MMT, Malkus J, Baxter S, Ishino S, Zhao Y, Sanchez-Gaytan B, Teunissen AJP, Frederico YCA, Tang J, Carlucci G, Lyashchenko S, Calcagno C, Karakatsanis N, Soultanidis G, Senders ML, Robson PM, Mani V, Ramachandran S, Lobatto ME, Hutten BA, Granada JF, Reiner T, Swirski FK, Nahrendorf M, Kjaer A, Fisher EA, Fayad ZA, Pérez-Medina C, Mulder WJM. Binderup T, et al. Among authors: fay f. Sci Transl Med. 2019 Aug 21;11(506):eaaw7736. doi: 10.1126/scitranslmed.aaw7736. Sci Transl Med. 2019. PMID: 31434756 Free PMC article.
Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance.
Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Pérez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J. Braza MS, et al. Among authors: fay f. Immunity. 2018 Nov 20;49(5):819-828.e6. doi: 10.1016/j.immuni.2018.09.008. Epub 2018 Nov 6. Immunity. 2018. PMID: 30413362 Free PMC article.
Author Correction: Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates.
Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R. Lameijer M, et al. Among authors: fay f. Nat Biomed Eng. 2018 Aug;2(8):623. doi: 10.1038/s41551-018-0281-3. Nat Biomed Eng. 2018. PMID: 31015637
HDL-mimetic PLGA nanoparticle to target atherosclerosis plaque macrophages.
Sanchez-Gaytan BL, Fay F, Lobatto ME, Tang J, Ouimet M, Kim Y, van der Staay SE, van Rijs SM, Priem B, Zhang L, Fisher EA, Moore KJ, Langer R, Fayad ZA, Mulder WJ. Sanchez-Gaytan BL, et al. Among authors: fay f. Bioconjug Chem. 2015 Mar 18;26(3):443-51. doi: 10.1021/bc500517k. Epub 2015 Feb 13. Bioconjug Chem. 2015. PMID: 25650634 Free PMC article.
Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.
Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ. Tang J, et al. Among authors: fay f. Sci Adv. 2015 Apr;1(3):e1400223. doi: 10.1126/sciadv.1400223. Sci Adv. 2015. PMID: 26295063 Free PMC article.
243 results