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Page 1
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.
Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts SABM, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slütter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E. Seijkens TTP, et al. Among authors: vriend g. J Am Coll Cardiol. 2018 Feb 6;71(5):527-542. doi: 10.1016/j.jacc.2017.11.055. J Am Coll Cardiol. 2018. PMID: 29406859 Free PMC article.
Discovery of small molecule CD40-TRAF6 inhibitors.
Zarzycka B, Seijkens T, Nabuurs SB, Ritschel T, Grommes J, Soehnlein O, Schrijver R, van Tiel CM, Hackeng TM, Weber C, Giehler F, Kieser A, Lutgens E, Vriend G, Nicolaes GA. Zarzycka B, et al. Among authors: vriend g. J Chem Inf Model. 2015 Feb 23;55(2):294-307. doi: 10.1021/ci500631e. Epub 2015 Jan 27. J Chem Inf Model. 2015. PMID: 25622654
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, Klotzsche-von Ameln A, Gijbels M, Noelle R, Boon L, Hackeng T, Schulte KM, Xu A, Vriend G, Nabuurs S, Chung KJ, Willems van Dijk K, Rensen PC, Gerdes N, de Winther M, Block NL, Schally AV, Weber C, Bornstein SR, Nicolaes G, Chavakis T, Lutgens E. Chatzigeorgiou A, et al. Among authors: vriend g. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2686-91. doi: 10.1073/pnas.1400419111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24492375 Free PMC article.
iPPI-DB: an online database of modulators of protein-protein interactions.
Labbé CM, Kuenemann MA, Zarzycka B, Vriend G, Nicolaes GA, Lagorce D, Miteva MA, Villoutreix BO, Sperandio O. Labbé CM, et al. Among authors: vriend g. Nucleic Acids Res. 2016 Jan 4;44(D1):D542-7. doi: 10.1093/nar/gkv982. Epub 2015 Oct 1. Nucleic Acids Res. 2016. PMID: 26432833 Free PMC article.
Structural anomalies in a published NMR-derived structure of IRAK-M.
Poelman H, Ippel H, Gürkan B, Boelens R, Vriend G, Veer CV', Lutgens E, Nicolaes GAF. Poelman H, et al. Among authors: vriend g. J Mol Graph Model. 2022 Mar;111:108061. doi: 10.1016/j.jmgm.2021.108061. Epub 2021 Nov 5. J Mol Graph Model. 2022. PMID: 34837785
Homology modeling.
Krieger E, Nabuurs SB, Vriend G. Krieger E, et al. Among authors: vriend g. Methods Biochem Anal. 2003;44:509-23. doi: 10.1002/0471721204.ch25. Methods Biochem Anal. 2003. PMID: 12647402 Review. No abstract available.
Quantitative evaluation of experimental NMR restraints.
Nabuurs SB, Spronk CA, Krieger E, Maassen H, Vriend G, Vuister GW. Nabuurs SB, et al. Among authors: vriend g. J Am Chem Soc. 2003 Oct 1;125(39):12026-34. doi: 10.1021/ja035440f. J Am Chem Soc. 2003. PMID: 14505424
DRESS: a database of REfined solution NMR structures.
Nabuurs SB, Nederveen AJ, Vranken W, Doreleijers JF, Bonvin AM, Vuister GW, Vriend G, Spronk CA. Nabuurs SB, et al. Among authors: vriend g. Proteins. 2004 May 15;55(3):483-6. doi: 10.1002/prot.20118. Proteins. 2004. PMID: 15103611
248 results