de Winther MPJ - Search Results

1

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.

Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts SABM, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slütter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E. Seijkens TTP, et al. Among authors: de winther mpj. J Am Coll Cardiol. 2018 Feb 6;71(5):527-542. doi: 10.1016/j.jacc.2017.11.055. J Am Coll Cardiol. 2018. PMID: 29406859 Free PMC article.

2

Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice.

de Winther MP, Gijbels MJ, van Dijk KW, van Gorp PJ, suzuki H, Kodama T, Frants RR, Havekes LM, Hofker MH. de Winther MP, et al. Atherosclerosis. 1999 Jun;144(2):315-21. doi: 10.1016/s0021-9150(98)00332-3. Atherosclerosis. 1999. PMID: 10407492

3

Transgenic mouse models to study the role of the macrophage scavenger receptor class A in atherosclerosis.

De Winther MP, Gijbels MJ, Van Dijk KW, Havekes LM, Hofker MH. De Winther MP, et al. Int J Tissue React. 2000;22(2-3):85-91. Int J Tissue React. 2000. PMID: 10937358 Review.

4

Leukocyte CD40L deficiency affects the CD25(+) CD4 T cell population but does not affect atherosclerosis.

Smook ML, Heeringa P, Damoiseaux JG, Daemen MJ, de Winther MP, Gijbels MJ, Beckers L, Lutgens E, Tervaert JW. Smook ML, et al. Atherosclerosis. 2005 Dec;183(2):275-82. doi: 10.1016/j.atherosclerosis.2005.03.051. Epub 2005 Jul 5. Atherosclerosis. 2005. PMID: 16002076

5

Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation.

Lutgens E, Lutgens SP, Faber BC, Heeneman S, Gijbels MM, de Winther MP, Frederik P, van der Made I, Daugherty A, Sijbers AM, Fisher A, Long CJ, Saftig P, Black D, Daemen MJ, Cleutjens KB. Lutgens E, et al. Circulation. 2006 Jan 3;113(1):98-107. doi: 10.1161/CIRCULATIONAHA.105.561449. Epub 2005 Dec 19. Circulation. 2006. PMID: 16365196

6

Gene profiling of cathepsin K deficiency in atherogenesis: profibrotic but lipogenic.

Lutgens SP, Kisters N, Lutgens E, van Haaften RI, Evelo CT, de Winther MP, Saftig P, Daemen MJ, Heeneman S, Cleutjens KB. Lutgens SP, et al. J Pathol. 2006 Nov;210(3):334-43. doi: 10.1002/path.2054. J Pathol. 2006. PMID: 16972305

7

Disruption of hedgehog signalling in ApoE - /- mice reduces plasma lipid levels, but increases atherosclerosis due to enhanced lipid uptake by macrophages.

Beckers L, Heeneman S, Wang L, Burkly LC, Rousch MM, Davidson NO, Gijbels MJ, de Winther MP, Daemen MJ, Lutgens E. Beckers L, et al. J Pathol. 2007 Aug;212(4):420-8. doi: 10.1002/path.2193. J Pathol. 2007. PMID: 17573667

8

Macrophage-specific expression of mannose-binding lectin controls atherosclerosis in low-density lipoprotein receptor-deficient mice.

Matthijsen RA, de Winther MP, Kuipers D, van der Made I, Weber C, Herias MV, Gijbels MJ, Buurman WA. Matthijsen RA, et al. Circulation. 2009 Apr 28;119(16):2188-95. doi: 10.1161/CIRCULATIONAHA.108.830661. Epub 2009 Apr 20. Circulation. 2009. PMID: 19380618

9

Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice.

Xanthoulea S, Thelen M, Pöttgens C, Gijbels MJ, Lutgens E, de Winther MP. Xanthoulea S, et al. PLoS One. 2009 Jul 7;4(7):e6113. doi: 10.1371/journal.pone.0006113. PLoS One. 2009. PMID: 19582157 Free PMC article.

10

The IgM response to modified LDL in experimental atherosclerosis: hypochlorite-modified LDL IgM antibodies versus classical natural T15 IgM antibodies.

van Leeuwen M, Damoiseaux J, Duijvestijn A, Heeringa P, Gijbels M, de Winther M, Tervaert JW. van Leeuwen M, et al. Ann N Y Acad Sci. 2009 Sep;1173:274-9. doi: 10.1111/j.1749-6632.2009.04657.x. Ann N Y Acad Sci. 2009. PMID: 19758162

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