Ray SS - Search Results

1

Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors.

Suebsuwong C, Pinkas DM, Ray SS, Bufton JC, Dai B, Bullock AN, Degterev A, Cuny GD. Suebsuwong C, et al. Among authors: ray ss. Bioorg Med Chem Lett. 2018 Feb 15;28(4):577-583. doi: 10.1016/j.bmcl.2018.01.044. Epub 2018 Jan 31. Bioorg Med Chem Lett. 2018. PMID: 29409752 Free PMC article.

2

Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors.

Canning P, Ruan Q, Schwerd T, Hrdinka M, Maki JL, Saleh D, Suebsuwong C, Ray S, Brennan PE, Cuny GD, Uhlig HH, Gyrd-Hansen M, Degterev A, Bullock AN. Canning P, et al. Chem Biol. 2015 Sep 17;22(9):1174-84. doi: 10.1016/j.chembiol.2015.07.017. Epub 2015 Aug 27. Chem Biol. 2015. PMID: 26320862 Free PMC article.

3

Fluorescence polarization assay for inhibitors of the kinase domain of receptor interacting protein 1.

Maki JL, Smith EE, Teng X, Ray SS, Cuny GD, Degterev A. Maki JL, et al. Among authors: ray ss. Anal Biochem. 2012 Aug 15;427(2):164-74. doi: 10.1016/j.ab.2012.05.019. Epub 2012 May 29. Anal Biochem. 2012. PMID: 22658960 Free PMC article.

4

Discovery of LRRK2 inhibitors using sequential in silico joint pharmacophore space (JPS) and ensemble docking.

Lang CA, Ray SS, Liu M, Singh AK, Cuny GD. Lang CA, et al. Among authors: ray ss. Bioorg Med Chem Lett. 2015 Jul 1;25(13):2713-9. doi: 10.1016/j.bmcl.2015.04.027. Epub 2015 Apr 16. Bioorg Med Chem Lett. 2015. PMID: 25998502

5

Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH.

Kirubakaran S, Gorla SK, Sharling L, Zhang M, Liu X, Ray SS, Macpherson IS, Striepen B, Hedstrom L, Cuny GD. Kirubakaran S, et al. Among authors: ray ss. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1985-8. doi: 10.1016/j.bmcl.2012.01.029. Epub 2012 Jan 24. Bioorg Med Chem Lett. 2012. PMID: 22310229 Free PMC article.

6

Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors.

Cuny GD, Ulyanova NP, Patnaik D, Liu JF, Lin X, Auerbach K, Ray SS, Xian J, Glicksman MA, Stein RL, Higgins JM. Cuny GD, et al. Among authors: ray ss. Bioorg Med Chem Lett. 2012 Mar 1;22(5):2015-9. doi: 10.1016/j.bmcl.2012.01.028. Epub 2012 Jan 28. Bioorg Med Chem Lett. 2012. PMID: 22335895 Free PMC article.

7

Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors: a patent and scientific literature review (2002-2016).

Cuny GD, Suebsuwong C, Ray SS. Cuny GD, et al. Among authors: ray ss. Expert Opin Ther Pat. 2017 Jun;27(6):677-690. doi: 10.1080/13543776.2017.1280463. Epub 2017 Jan 27. Expert Opin Ther Pat. 2017. PMID: 28074661 Review.

8

Improving binding specificity of pharmacological chaperones that target mutant superoxide dismutase-1 linked to familial amyotrophic lateral sclerosis using computational methods.

Nowak RJ, Cuny GD, Choi S, Lansbury PT, Ray SS. Nowak RJ, et al. Among authors: ray ss. J Med Chem. 2010 Apr 8;53(7):2709-18. doi: 10.1021/jm901062p. J Med Chem. 2010. PMID: 20232802 Free PMC article.

9

Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1.

Najjar M, Suebsuwong C, Ray SS, Thapa RJ, Maki JL, Nogusa S, Shah S, Saleh D, Gough PJ, Bertin J, Yuan J, Balachandran S, Cuny GD, Degterev A. Najjar M, et al. Among authors: ray ss. Cell Rep. 2015 Mar 24;10(11):1850-60. doi: 10.1016/j.celrep.2015.02.052. Cell Rep. 2015. PMID: 25801024 Free PMC article.

10

Type II kinase inhibitors show an unexpected inhibition mode against Parkinson's disease-linked LRRK2 mutant G2019S.

Liu M, Bender SA, Cuny GD, Sherman W, Glicksman M, Ray SS. Liu M, et al. Among authors: ray ss. Biochemistry. 2013 Mar 12;52(10):1725-36. doi: 10.1021/bi3012077. Epub 2013 Mar 1. Biochemistry. 2013. PMID: 23379419 Free PMC article.

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