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Targeting hepatic glutaminase activity to ameliorate hyperglycemia.
Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ. Miller RA, et al. Among authors: birnbaum mj. Nat Med. 2018 May;24(4):518-524. doi: 10.1038/nm.4514. Epub 2018 Mar 26. Nat Med. 2018. PMID: 29578539 Free PMC article.
Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction.
Gutierrez JA, Liu W, Perez S, Xing G, Sonnenberg G, Kou K, Blatnik M, Allen R, Weng Y, Vera NB, Chidsey K, Bergman A, Somayaji V, Crowley C, Clasquin MF, Nigam A, Fulham MA, Erion DM, Ross TT, Esler WP, Magee TV, Pfefferkorn JA, Bence KK, Birnbaum MJ, Tesz GJ. Gutierrez JA, et al. Among authors: birnbaum mj. Mol Metab. 2021 Jun;48:101196. doi: 10.1016/j.molmet.2021.101196. Epub 2021 Mar 3. Mol Metab. 2021. PMID: 33667726 Free PMC article. Clinical Trial.
Molecular aspects of fructose metabolism and metabolic disease.
Herman MA, Birnbaum MJ. Herman MA, et al. Among authors: birnbaum mj. Cell Metab. 2021 Dec 7;33(12):2329-2354. doi: 10.1016/j.cmet.2021.09.010. Epub 2021 Oct 6. Cell Metab. 2021. PMID: 34619074 Free PMC article. Review.
Metabolic drivers of non-alcoholic fatty liver disease.
Bence KK, Birnbaum MJ. Bence KK, et al. Among authors: birnbaum mj. Mol Metab. 2021 Aug;50:101143. doi: 10.1016/j.molmet.2020.101143. Epub 2020 Dec 17. Mol Metab. 2021. PMID: 33346069 Free PMC article. Review.
255 results