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Page 1
New thiophene-acridine compounds: Synthesis, antileishmanial activity, DNA binding, chemometric, and molecular docking studies.
de Lima Serafim V, Félix MB, Frade Silva DK, Rodrigues KADF, Andrade PN, de Almeida SMV, de Albuquerque Dos Santos S, de Oliveira JF, de Lima MDCA, Mendonça-Junior FJB, Scotti MT, de Oliveira MR, de Moura RO. de Lima Serafim V, et al. Among authors: de almeida smv, de moura ro, de albuquerque dos santos s, de oliveira mr, de oliveira jf, de lima mdca. Chem Biol Drug Des. 2018 Jun;91(6):1141-1155. doi: 10.1111/cbdd.13176. Epub 2018 Mar 25. Chem Biol Drug Des. 2018. PMID: 29415325
Ultrastructural Assessment of 2-(acridin-9-ylmethylene)-N-phenylhydrazinecarbothioamide activity on human breast adenocarcinoma cells.
de Almeida SMV, da Silva LPBG, de Lima LRA, Longato GB, Padilha RJR, Alves LC, Brayner FA, Ruiz ALTG, de Carvalho JE, Beltrão EIC, de Lima MDCA, de Carvalho Júnior LB. de Almeida SMV, et al. Among authors: de carvalho junior lb, de lima lra, de carvalho je, de lima mdca. Micron. 2016 Nov;90:114-122. doi: 10.1016/j.micron.2016.08.009. Epub 2016 Aug 30. Micron. 2016. PMID: 27668344
Thiosemicarbazones and 4-thiazolidinones indole-based derivatives: Synthesis, evaluation of antiproliferative activity, cell death mechanisms and topoisomerase inhibition assay.
de Oliveira JF, Lima TS, Vendramini-Costa DB, de Lacerda Pedrosa SCB, Lafayette EA, da Silva RMF, de Almeida SMV, de Moura RO, Ruiz ALTG, de Carvalho JE, de Lima MDCA. de Oliveira JF, et al. Among authors: de almeida smv, de moura ro, de lacerda pedrosa scb, de carvalho je, de lima mdca. Eur J Med Chem. 2017 Aug 18;136:305-314. doi: 10.1016/j.ejmech.2017.05.023. Epub 2017 May 8. Eur J Med Chem. 2017. PMID: 28505535
Synthesis of novel indole derivatives as promising DNA-binding agents and evaluation of antitumor and antitopoisomerase I activities.
Lafayette EA, de Almeida SMV, Cavalcanti Santos RV, de Oliveira JF, Amorim CADC, da Silva RMF, Pitta MGDR, Pitta IDR, de Moura RO, de Carvalho Júnior LB, de Melo Rêgo MJB, de Lima MDCA. Lafayette EA, et al. Among authors: de almeida smv, de moura ro, de carvalho junior lb, de melo rego mjb, de oliveira jf, de lima mdca. Eur J Med Chem. 2017 Aug 18;136:511-522. doi: 10.1016/j.ejmech.2017.05.012. Epub 2017 May 4. Eur J Med Chem. 2017. PMID: 28531811
DNA binding and Topoisomerase inhibition: How can these mechanisms be explored to design more specific anticancer agents?
de Almeida SMV, Ribeiro AG, de Lima Silva GC, Ferreira Alves JE, Beltrão EIC, de Oliveira JF, de Carvalho LB Junior, Alves de Lima MDC. de Almeida SMV, et al. Among authors: de carvalho lb junior, de lima silva gc, de oliveira jf. Biomed Pharmacother. 2017 Dec;96:1538-1556. doi: 10.1016/j.biopha.2017.11.054. Epub 2017 Nov 22. Biomed Pharmacother. 2017. PMID: 29174576 Review.
Synthesis, DNA and protein interactions and human topoisomerase inhibition of novel Spiroacridine derivatives.
Gouveia RG, Ribeiro AG, Segundo MÂSP, de Oliveira JF, de Lima MDCA, de Lima Souza TRC, de Almeida SMV, de Moura RO. Gouveia RG, et al. Among authors: de almeida smv, de moura ro, de lima souza trc, de oliveira jf, de lima mdca. Bioorg Med Chem. 2018 Dec 1;26(22):5911-5921. doi: 10.1016/j.bmc.2018.10.038. Epub 2018 Oct 29. Bioorg Med Chem. 2018. PMID: 30420325
5-Nitro-Thiophene-Thiosemicarbazone Derivatives Present Antitumor Activity Mediated by Apoptosis and DNA Intercalation.
Roque Marques KM, do Desterro MR, de Arruda SM, de Araújo Neto LN, do Carmo Alves de Lima M, de Almeida SMV, da Silva ECD, de Aquino TM, da Silva-Júnior EF, de Araújo-Júnior JX, de M Silva M, de A Dantas MD, Santos JCC, Figueiredo IM, Bazin MA, Marchand P, da Silva TG, Mendonça Junior FJB. Roque Marques KM, et al. Among authors: de almeida smv. Curr Top Med Chem. 2019;19(13):1075-1091. doi: 10.2174/1568026619666190621120304. Curr Top Med Chem. 2019. PMID: 31223089
Topoisomerase inhibition and albumin interaction studies of acridine-thiosemicarbazone derivatives.
da Silva Filho FA, de Freitas Souza T, Ribeiro AG, Alves JEF, de Oliveira JF, de Lima Souza TRC, de Moura RO, do Carmo Alves de Lima M, de Carvalho Junior LB, de Almeida SMV. da Silva Filho FA, et al. Among authors: de almeida smv. Int J Biol Macromol. 2019 Oct 1;138:582-589. doi: 10.1016/j.ijbiomac.2019.07.097. Epub 2019 Jul 16. Int J Biol Macromol. 2019. PMID: 31323270 Free article.
23 results