Vernon RM - Search Results

1

Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

Vernon RM, Chong PA, Tsang B, Kim TH, Bah A, Farber P, Lin H, Forman-Kay JD. Vernon RM, et al. Elife. 2018 Feb 9;7:e31486. doi: 10.7554/eLife.31486. Elife. 2018. PMID: 29424691 Free PMC article.

2

Solution structure of a minor and transiently formed state of a T4 lysozyme mutant.

Bouvignies G, Vallurupalli P, Hansen DF, Correia BE, Lange O, Bah A, Vernon RM, Dahlquist FW, Baker D, Kay LE. Bouvignies G, et al. Among authors: vernon rm. Nature. 2011 Aug 21;477(7362):111-4. doi: 10.1038/nature10349. Nature. 2011. PMID: 21857680 Free PMC article.

3

Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator.

Hudson RP, Chong PA, Protasevich II, Vernon R, Noy E, Bihler H, An JL, Kalid O, Sela-Culang I, Mense M, Senderowitz H, Brouillette CG, Forman-Kay JD. Hudson RP, et al. J Biol Chem. 2012 Aug 17;287(34):28480-94. doi: 10.1074/jbc.M112.371138. Epub 2012 Jun 21. J Biol Chem. 2012. PMID: 22722932 Free PMC article.

4

Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch.

Bah A, Vernon RM, Siddiqui Z, Krzeminski M, Muhandiram R, Zhao C, Sonenberg N, Kay LE, Forman-Kay JD. Bah A, et al. Among authors: vernon rm. Nature. 2015 Mar 5;519(7541):106-9. doi: 10.1038/nature13999. Epub 2014 Dec 22. Nature. 2015. PMID: 25533957

5

Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization.

Chong PA, Farber PJ, Vernon RM, Hudson RP, Mittermaier AK, Forman-Kay JD. Chong PA, et al. Among authors: vernon rm. J Biol Chem. 2015 Sep 18;290(38):22862-78. doi: 10.1074/jbc.M115.641134. Epub 2015 Jul 6. J Biol Chem. 2015. PMID: 26149808 Free PMC article.

6

Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations.

Vernon RM, Chong PA, Lin H, Yang Z, Zhou Q, Aleksandrov AA, Dawson JE, Riordan JR, Brouillette CG, Thibodeau PH, Forman-Kay JD. Vernon RM, et al. J Biol Chem. 2017 Aug 25;292(34):14147-14164. doi: 10.1074/jbc.M116.772335. Epub 2017 Jun 27. J Biol Chem. 2017. PMID: 28655774 Free PMC article.

7

RGG/RG Motif Regions in RNA Binding and Phase Separation.

Chong PA, Vernon RM, Forman-Kay JD. Chong PA, et al. Among authors: vernon rm. J Mol Biol. 2018 Nov 2;430(23):4650-4665. doi: 10.1016/j.jmb.2018.06.014. Epub 2018 Jun 15. J Mol Biol. 2018. PMID: 29913160 Review.

8

Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation.

Tsang B, Arsenault J, Vernon RM, Lin H, Sonenberg N, Wang LY, Bah A, Forman-Kay JD. Tsang B, et al. Among authors: vernon rm. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4218-4227. doi: 10.1073/pnas.1814385116. Epub 2019 Feb 14. Proc Natl Acad Sci U S A. 2019. PMID: 30765518 Free PMC article.

9

Temperature, Hydrostatic Pressure, and Osmolyte Effects on Liquid-Liquid Phase Separation in Protein Condensates: Physical Chemistry and Biological Implications.

Cinar H, Fetahaj Z, Cinar S, Vernon RM, Chan HS, Winter RHA. Cinar H, et al. Among authors: vernon rm. Chemistry. 2019 Oct 11;25(57):13049-13069. doi: 10.1002/chem.201902210. Epub 2019 Aug 22. Chemistry. 2019. PMID: 31237369 Review.

10

First-generation predictors of biological protein phase separation.

Vernon RM, Forman-Kay JD. Vernon RM, et al. Curr Opin Struct Biol. 2019 Oct;58:88-96. doi: 10.1016/j.sbi.2019.05.016. Epub 2019 Jun 25. Curr Opin Struct Biol. 2019. PMID: 31252218 Review.

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