Light PE - Search Results

1

Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2.

Zheng W, Cai R, Hofmann L, Nesin V, Hu Q, Long W, Fatehi M, Liu X, Hussein S, Kong T, Li J, Light PE, Tang J, Flockerzi V, Tsiokas L, Chen XZ. Zheng W, et al. Among authors: light pe. Cell Rep. 2018 Feb 6;22(6):1560-1573. doi: 10.1016/j.celrep.2018.01.042. Cell Rep. 2018. PMID: 29425510 Free PMC article.

2

The ATP-sensitive K(+) channel ABCC8 S1369A type 2 diabetes risk variant increases MgATPase activity.

Fatehi M, Raja M, Carter C, Soliman D, Holt A, Light PE. Fatehi M, et al. Among authors: light pe. Diabetes. 2012 Jan;61(1):241-9. doi: 10.2337/db11-0371. Diabetes. 2012. PMID: 22187380 Free PMC article.

3

Pharmacogenomic analysis of ATP-sensitive potassium channels coexpressing the common type 2 diabetes risk variants E23K and S1369A.

Lang VY, Fatehi M, Light PE. Lang VY, et al. Among authors: light pe. Pharmacogenet Genomics. 2012 Mar;22(3):206-14. doi: 10.1097/FPC.0b013e32835001e7. Pharmacogenet Genomics. 2012. PMID: 22209866

4

Late sodium current inhibition alone with ranolazine is sufficient to reduce ischemia- and cardiac glycoside-induced calcium overload and contractile dysfunction mediated by reverse-mode sodium/calcium exchange.

Soliman D, Wang L, Hamming KS, Yang W, Fatehi M, Carter CC, Clanachan AS, Light PE. Soliman D, et al. Among authors: light pe. J Pharmacol Exp Ther. 2012 Nov;343(2):325-32. doi: 10.1124/jpet.112.196949. Epub 2012 Aug 9. J Pharmacol Exp Ther. 2012. PMID: 22879384

5

Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity.

Fatehi M, Carter CR, Youssef N, Hunter BE, Holt A, Light PE. Fatehi M, et al. Among authors: light pe. Biosci Rep. 2015 Jul 7;35(4):e00238. doi: 10.1042/BSR20150143. Biosci Rep. 2015. PMID: 26181369 Free PMC article.

6

The mechano-sensitivity of cardiac ATP-sensitive potassium channels is mediated by intrinsic MgATPase activity.

Fatehi M, Carter CC, Youssef N, Light PE. Fatehi M, et al. Among authors: light pe. J Mol Cell Cardiol. 2017 Jul;108:34-41. doi: 10.1016/j.yjmcc.2017.05.004. Epub 2017 May 5. J Mol Cell Cardiol. 2017. PMID: 28483598

7

Identification and characterization of hydrophobic gate residues in TRP channels.

Zheng W, Hu R, Cai R, Hofmann L, Hu Q, Fatehi M, Long W, Kong T, Tang J, Light P, Flockerzi V, Cao Y, Chen XZ. Zheng W, et al. FASEB J. 2018 Feb;32(2):639-653. doi: 10.1096/fj.201700599RR. Epub 2018 Jan 4. FASEB J. 2018. PMID: 28970257

8

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis.

Ondrusova K, Fatehi M, Barr A, Czarnecka Z, Long W, Suzuki K, Campbell S, Philippaert K, Hubert M, Tredget E, Kwan P, Touret N, Wabitsch M, Lee KY, Light PE. Ondrusova K, et al. Among authors: light pe. Sci Rep. 2017 Nov 27;7(1):16332. doi: 10.1038/s41598-017-16689-4. Sci Rep. 2017. PMID: 29180820 Free PMC article.

9

Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel.

Long W, Fatehi M, Soni S, Panigrahi R, Philippaert K, Yu Y, Kelly R, Boonen B, Barr A, Golec D, Campbell SA, Ondrusova K, Hubert M, Baldwin T, Lemieux MJ, Light PE. Long W, et al. Among authors: light pe. J Physiol. 2020 Oct;598(19):4321-4338. doi: 10.1113/JP279961. Epub 2020 Aug 13. J Physiol. 2020. PMID: 32721035 Free PMC article.

10

TRPV1 channels as a newly identified target for vitamin D.

Long W, Johnson J, Kalyaanamoorthy S, Light P. Long W, et al. Channels (Austin). 2021 Dec;15(1):360-374. doi: 10.1080/19336950.2021.1905248. Channels (Austin). 2021. PMID: 33825665 Free PMC article. Review.

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