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High-Content Microfluidic Screening Platform Used To Identify σ2R/Tmem97 Binding Ligands that Reduce Age-Dependent Neurodegeneration in C. elegans SC_APP Model.
Mondal S, Hegarty E, Sahn JJ, Scott LL, Gökçe SK, Martin C, Ghorashian N, Satarasinghe PN, Iyer S, Sae-Lee W, Hodges TR, Pierce JT, Martin SF, Ben-Yakar A. Mondal S, et al. Among authors: sahn jj. ACS Chem Neurosci. 2018 May 16;9(5):1014-1026. doi: 10.1021/acschemneuro.7b00428. Epub 2018 Feb 23. ACS Chem Neurosci. 2018. PMID: 29426225 Free PMC article.
Identification of the gene that codes for the σ2 receptor.
Alon A, Schmidt HR, Wood MD, Sahn JJ, Martin SF, Kruse AC. Alon A, et al. Among authors: sahn jj. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7160-7165. doi: 10.1073/pnas.1705154114. Epub 2017 May 30. Proc Natl Acad Sci U S A. 2017. PMID: 28559337 Free PMC article.
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