Rodrigues AD - Search Results

1

Role of Hepatic Organic Anion Transporter 2 in the Pharmacokinetics of R- and S-Warfarin: In Vitro Studies and Mechanistic Evaluation.

Bi YA, Lin J, Mathialagan S, Tylaska L, Callegari E, Rodrigues AD, Varma MVS. Bi YA, et al. Among authors: rodrigues ad. Mol Pharm. 2018 Mar 5;15(3):1284-1295. doi: 10.1021/acs.molpharmaceut.7b01108. Epub 2018 Feb 20. Mol Pharm. 2018. PMID: 29433307

2

Screening of drug candidates for their drug--drug interaction potential.

Rodrigues AD, Lin JH. Rodrigues AD, et al. Curr Opin Chem Biol. 2001 Aug;5(4):396-401. doi: 10.1016/s1367-5931(00)00220-9. Curr Opin Chem Biol. 2001. PMID: 11470602 Review.

3

Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide.

Varma MV, Lin J, Bi YA, Kimoto E, Rodrigues AD. Varma MV, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2015 Jul;43(7):1108-18. doi: 10.1124/dmd.115.064303. Epub 2015 May 4. Drug Metab Dispos. 2015. PMID: 25941268

4

Transporter-Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug-Drug Interactions of Montelukast.

Varma MV, Kimoto E, Scialis R, Bi Y, Lin J, Eng H, Kalgutkar AS, El-Kattan AF, Rodrigues AD, Tremaine LM. Varma MV, et al. Among authors: rodrigues ad. Clin Pharmacol Ther. 2017 Mar;101(3):406-415. doi: 10.1002/cpt.520. Epub 2016 Nov 18. Clin Pharmacol Ther. 2017. PMID: 27648490

5

Organic Anion Transporter 2: An Enigmatic Human Solute Carrier.

Shen H, Lai Y, Rodrigues AD. Shen H, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2017 Feb;45(2):228-236. doi: 10.1124/dmd.116.072264. Epub 2016 Nov 21. Drug Metab Dispos. 2017. PMID: 27872146 Review.

6

Extended Clearance Classification System (ECCS) informed approach for evaluating investigational drugs as substrates of drug transporters.

Varma MV, El-Kattan AF, Feng B, Steyn SJ, Maurer TS, Scott DO, Rodrigues AD, Tremaine LM. Varma MV, et al. Among authors: rodrigues ad. Clin Pharmacol Ther. 2017 Jul;102(1):33-36. doi: 10.1002/cpt.595. Epub 2017 Feb 3. Clin Pharmacol Ther. 2017. PMID: 27984654 No abstract available.

7

Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes.

Bi YA, Scialis RJ, Lazzaro S, Mathialagan S, Kimoto E, Keefer J, Zhang H, Vildhede AM, Costales C, Rodrigues AD, Tremaine LM, Varma MVS. Bi YA, et al. Among authors: rodrigues ad. AAPS J. 2017 May;19(3):787-796. doi: 10.1208/s12248-017-0051-2. Epub 2017 Feb 10. AAPS J. 2017. PMID: 28188574

8

Erratum to: Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes.

Bi YA, Scialis RJ, Lazzaro S, Mathialagan S, Kimoto E, Keefer J, Zhang H, Vildhede AM, Costales C, Rodrigues AD, Tremaine LM, Varma MVS. Bi YA, et al. Among authors: rodrigues ad. AAPS J. 2017 May;19(3):882. doi: 10.1208/s12248-017-0061-0. AAPS J. 2017. PMID: 28233243 No abstract available.

9

Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides.

Thakare R, Gao H, Kosa RE, Bi YA, Varma MVS, Cerny MA, Sharma R, Kuhn M, Huang B, Liu Y, Yu A, Walker GS, Niosi M, Tremaine L, Alnouti Y, Rodrigues AD. Thakare R, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2017 Jul;45(7):721-733. doi: 10.1124/dmd.117.075275. Epub 2017 Apr 10. Drug Metab Dispos. 2017. PMID: 28396527

10

Evaluation of Renal Transporter Inhibition Using Creatinine as a Substrate In Vitro to Assess the Clinical Risk of Elevated Serum Creatinine.

Mathialagan S, Rodrigues AD, Feng B. Mathialagan S, et al. Among authors: rodrigues ad. J Pharm Sci. 2017 Sep;106(9):2535-2541. doi: 10.1016/j.xphs.2017.04.009. Epub 2017 Apr 14. J Pharm Sci. 2017. PMID: 28416419

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